Health and Parenting
Melatonin for kids: Is it effective? Is it safe?
You’ve heard melatonin — an over-the-counter hormone supplement — can help with insomnia. Perhaps your pediatrician has recommended it. But is it really beneficial, and can your child take it safely? A recent study from the Centers for Disease Control and Prevention (CDC) raises some concerns. It found an alarming six-fold increase in the past ... Read More about Melatonin for kids: Is it effective? Is it safe?
Research
Exploiting a vulnerability in an aggressive leukemia
Survival has improved greatly in children with acute lymphocytic leukemia (ALL). But a certain form of ALL that occurs mostly in babies is still very lethal, with a survival rate below 50 percent: B-cell acute lymphoblastic leukemia with rearrangements of the mixed lineage leukemia gene, or MLL B-ALL. “Something about the biology of this type ... Read More about Exploiting a vulnerability in an aggressive leukemia
Patient Stories
Unstoppable: Cairo’s journey for kidney care began even before birth
Like lots of babies, Cairo Carter was born screaming — and his parents were thrilled. “We just wanted him to scream so we knew he could breathe,” explains his mother, Alaila. The family cried tears of joy and relief, but they understood that the moment was just the first step of a long journey. “We ... Read More about Unstoppable: Cairo’s journey for kidney care began even before birth
Patient Stories
From South Africa to Boston: Kyleigh’s four-year search for good heart health
Kyleigh Kista had three open-heart surgeries in just the first 18 months of her life. But instead of progressing, her health was rapidly deteriorating by the time she reached 3. Her doctors said there was little else they could do, except make her a candidate for a heart and lung transplant. It was shattering news ... Read More about From South Africa to Boston: Kyleigh’s four-year search for good heart health
Research
Previous COVID-19 or MIS-C does not protect kids from Omicron
You would think that having had COVID-19 once, you’d have antibodies that would protect you against repeat infections. But studies of adults have shown that Omicron doesn’t go by that logic. A new study, led by Dr. Adrienne Randolph of Boston Children’s Hospital and Dr. Surender Khurana of the Food and Drug Administration, confirms that ... Read More about Previous COVID-19 or MIS-C does not protect kids from Omicron
Research
Getting to the heart of heart muscle function
Every heart muscle cell, or cardiomyocyte, is studded with tiny, intricate structures called dyads. The dyads are like orchestra conductors: They coordinate incoming electrical signals with release of calcium in the muscle, triggering contraction. When dyads work properly, the different segments of heart muscle contract in unison; when they don’t, heartbeats may be too weak ... Read More about Getting to the heart of heart muscle function
Research
Cell therapy for lung disease? Proof-of-concept study shows promise
Many serious pulmonary diseases, including genetic lung diseases, lack an effective treatment other than the most extreme: lung transplant. A team at Boston Children’s Hospital envisions a much better option: cell therapy, using lung stem cells created from patients’ own cells to repair or replace damaged lung tissue. For patients with genetic lung diseases, the ... Read More about Cell therapy for lung disease? Proof-of-concept study shows promise
Research
Old vaccine, new tricks? Unlocking the BCG vaccine’s potential
Could a century-old vaccine offer clues for designing the vaccines of tomorrow? Ofer Levy, MD, PhD, director of the Precision Vaccines Program at Boston Children’s Hospital, wants to find out. One of the world’s oldest and most widely used vaccines, the Bacille Calmette-Guérin (BCG) tuberculosis vaccine may at first seem like an unlikely source of ... Read More about Old vaccine, new tricks? Unlocking the BCG vaccine’s potential
Clinical Care
Undescended testicles: Why prompt referral is key
An estimated 3 percent of boys have undescended testicles at birth, making it a common problem encountered by pediatricians and urologists alike. Also known as cryptorchidism, an undescended testicle is one that hasn’t moved into its proper position in the scrotum before birth. Typically, only one testicle is affected, but in some cases, both may ... Read More about Undescended testicles: Why prompt referral is key
Our Community
Contributing to every level of care: Our Asian American and Pacific Islander community
People come to Boston Children’s Hospital to receive care from some of the best clinicians in the world. Yet the safe, nurturing environment that greets patients and families is the work of an extensive team. The Environmental Services team, for instance, works tirelessly to ensure every area of the hospital remains clean and welcoming. The ... Read More about Contributing to every level of care: Our Asian American and Pacific Islander community