Archive for newborn medicine
Bedside tech predicts newborns’ outcomes after therapeutic hypothermia
Hypoxic-ischemic encephalopathy (HIE), brain injury caused by oxygen deprivation around birth, is a common cause of admission to the neonatal intensive care unit. Therapeutic hypothermia is now becoming the standard treatment to minimize brain injury; cooling the newborn’s head or whole body for three days slows cellular metabolism and allows brain cells to avoid and ... Read More
Tagged: brain injury, imaging, neurology, newborn medicine, nicu
The sooner the better: An argument for fetal MRI before 16 weeks
To date, fetal magnetic resonance imaging (MRI) has been limited to the mid-second or the third trimester of pregnancy. This timing has been based on the belief that MRIs performed too early couldn’t produce diagnostic images because of the small fetal size and normal fetal motion. In addition, although practice guidelines indicate that first-trimester imaging ... Read More
Tagged: imaging, MFCC, newborn medicine, pregnancy
Advancing mother-child health globally: Grace Chan MD, MPH, PhD
First in an ongoing series profiling researchers at Boston Children’s Hospital. Globally, five million children die annually before the age of 5. Forty percent of these deaths are in the first month — and many are preventable. Grace Chan, MD, MPH, PhD, finds these numbers unacceptable. They contrast starkly with U.S. medicine, including at Boston ... Read More
Could gene therapy relieve post-hemorrhagic hydrocephalus?
Premature infants, especially very low birthweight babies, are at risk for intraventricular hemorrhage. A frequent complication of these brain bleeds is hydrocephalus, an accumulation of cerebrospinal fluid (CSF) in the brain ventricles that can gravely disrupt brain development. If hydrocephalus develops, a child may need shunt operations throughout life to manage the fluid buildup. Could ... Read More
Female leadership in neonatology: The value of mentorship
While the majority of neonatologists are women, women make up a far smaller proportion of neonatologists in leadership positions. A recent national survey led by Kristen Leeman, MD, in the Division of Newborn Medicine at Boston Children’s and Lindsay Johnston, MD, at Yale, finds that many female neonatologists face roadblocks to career development. They often ... Read More
Tagged: newborn medicine, research
Genetic sequencing may open doors for newborns with hypotonia
When a baby is born with low muscle tone (hypotonia), the future is hard to predict, and families have a lot of questions. How should neonatologists care for these infants? Findings from a recent review could help provide some answers, guide appropriate interventions, and in some cases open the way to custom treatments. Diagnosing a ... Read More
Optimizing care for bronchopulmonary dysplasia, infant by infant
Preterm newborns with bronchopulmonary dysplasia (BPD) can require ongoing mechanical ventilation to support their lungs. But babies with BPD aren’t just newborns with underdeveloped lungs. Each has a unique presentation. And every part of their care is important, with the ultimate goal of enabling them to grow, develop, and go home to their families. The ... Read More
Bringing Xavien home: One family’s journey with bronchopulmonary dysplasia
Xavien Velazquez is getting ready to celebrate his first birthday. It’s a milestone for every child but especially meaningful for this little boy who has spent more than half his life away from home receiving care for bronchopulmonary dysplasia (BPD), a chronic lung disease characterized by respiratory distress that is most often seen in newborns ... Read More
Using genetics to glimpse newborns’ future with congenital heart disease
Aside from infections, congenital heart disease (CHD) is the leading cause of infant mortality. Informed by babies she sees in the NICU, Sarah Morton, MD, PhD, attending physician in the Division of Newborn Medicine at Boston Children’s, has devoted her career to understanding CHD’s genetic causes. Her findings are shedding light on what parents and ... Read More
Bringing genomics to community NICUs
About a year and a half ago, Robert Rothstein, MD, FAAP encountered a baby with a pattern of facial features and clinical findings that suggested a genetic syndrome. The available tests couldn’t pinpoint a diagnosis, and the family wanted a more definitive answer. So Rothstein and his colleagues transferred the newborn from Baystate Medical Center ... Read More