ADHD drug class leads to fewer side effects in preschool children
About 2.4 percent of preschool-age children have an attention-deficit/hyperactivity disorder (ADHD) diagnosis. For these children, behavioral interventions intended to redirect a child or otherwise replace negative behaviors with positive ones are the first line of treatment. But what if symptoms linger, or are so severe that they interfere with a child’s social, emotional, and educational ... Read More
Taking treatment of long-gap esophageal atresia to the next level: Refining innovative techniques
The surgeons in the Esophageal and Airway Treatment Center at Boston Children’s Hospital are pioneers in developing and refining innovative surgical approaches to long-gap esophageal atresia, a condition in which a child’s esophagus develops in two separate segments that can’t be easily connected with surgery. Among these techniques are jejunal interposition and the Foker process. ... Read More
A coming wave of diabetes? The link with COVID-19
Researchers are observing a new long-term health concern in patients hospitalized with COVID-19 — an increase in new-onset hyperglycemia lasting months after infection. An Italian study found that about half of the patients admitted to the hospital for COVID-19 during the start of the pandemic had new cases of hyperglycemia, or high levels of blood ... Read More
Groundbreaking research helps advance treatment of rare, fast growing brain tumor
Researchers from the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center recently found that levels of a specific protein detected through a patient’s urine can track a tumor’s size and responsiveness to treatment in children with diffuse intrinsic pontine gliomas (DIPG). This discovery helps steer the course for more innovative and less invasive treatment options. Confronting ... Read More
Inspired by Chinese finger traps, an annuloplasty ring that grows with the child
This post is part of a series on innovations to treat valvular disease in children. Read our prior posts on transcatheter valve replacement and an expandable prosthetic heart valve. Prosthetic annuloplasty rings have improved the durability of heart valve repairs in adults. Implanted at the perimeter of dilated, leaky valves, they help keep the valve ... Read More
A ‘pump’ gene’s surprising role in early brain formation
In polymicrogyria, the cortex of the brain has many irregular, small folds (gyria) and disorganization of its layers. Many affected children have severe developmental delay, intellectual disabilities, and epilepsy, and many need to use a wheelchair. Mutations in several different genes can cause this “overfolding of the brain” condition. Key takeaways The gene ATP1A3, associated ... Read More