Making immunotherapy safe for AML
Acute myeloid leukemia (AML), the second most common leukemia in children, is hard to treat and has a five-year survival rate of just 65 to 70 percent, according to the American Cancer Society. While immunotherapies like monoclonal antibodies or CAR T-cell therapy are effective for certain blood cancers, they have not been possible in AML ... Read More
Uncertainty surrounds ACL treatment decisions in young athletes. It shouldn’t.
It’s an injury once seen mainly in adults, yet it’s become increasingly common in younger patients. From 2000 to 2020, the number of anterior cruciate ligament (ACL) tears in children and adolescents increased between three- and five-fold. For young athletes, an ACL tear spells six to nine months of downtime, heightened risk for secondary ACL ... Read More
EEG markers in early life could help predict and diagnose anxiety
Anxiety disorders are the most common mental health problem among children and adolescents and are a risk factor for adult disorders. Stress is a big factor — at home, at school, and from external factors like COVID-19 and climate change. But some children may be innately more susceptible to anxiety. New research at Boston Children’s ... Read More
Pioneering trial offers hope for late treatment of ‘lazy eye’
In children with amblyopia or “lazy eye,” one eye is weaker than the other for any of a number of reasons. It may not focus as well, it may be misaligned due to strabismus, or its vision may be obstructed by a cataract or a droopy eyelid. As a result, the brain starts to favor ... Read More
Hurdles in health care: Navigating insurance approvals
If you’ve ever struggled with your patient’s insurance company when it came to getting their prescription filled, you’re not alone. For patients with chronic conditions, including inflammatory bowel disease (IBD), newer drugs like biologics can be very effective — but also very expensive. As a result, many insurance companies have limited access to these medications ... Read More
Rapid DNA sequencing yields timely answers for infant epilepsy
Treating children with epilepsy has traditionally been a matter of trial and error, trying different drugs one after the other. In the one-third of patients for whom the drugs do not work and seizures continue, doctors consider brain surgery — if it can be done safely. Early in her career, Ann Poduri, MD, MPH, who ... Read More