Research
Getting to the heart of heart muscle function
Every heart muscle cell, or cardiomyocyte, is studded with tiny, intricate structures called dyads. The dyads are like orchestra conductors: They coordinate incoming electrical signals with release of calcium in the muscle, triggering contraction. When dyads work properly, the different segments of heart muscle contract in unison; when they don’t, heartbeats may be too weak ... Read More about Getting to the heart of heart muscle function
Research
Cell therapy for lung disease? Proof-of-concept study shows promise
Many serious pulmonary diseases, including genetic lung diseases, lack an effective treatment other than the most extreme: lung transplant. A team at Boston Children’s Hospital envisions a much better option: cell therapy, using lung stem cells created from patients’ own cells to repair or replace damaged lung tissue. For patients with genetic lung diseases, the ... Read More about Cell therapy for lung disease? Proof-of-concept study shows promise
Research
Old vaccine, new tricks? Unlocking the BCG vaccine’s potential
Could a century-old vaccine offer clues for designing the vaccines of tomorrow? Ofer Levy, MD, PhD, director of the Precision Vaccines Program at Boston Children’s Hospital, wants to find out. One of the world’s oldest and most widely used vaccines, the Bacille Calmette-Guérin (BCG) tuberculosis vaccine may at first seem like an unlikely source of ... Read More about Old vaccine, new tricks? Unlocking the BCG vaccine’s potential
Clinical Care
Undescended testicles: Why prompt referral is key
An estimated 3 percent of boys have undescended testicles at birth, making it a common problem encountered by pediatricians and urologists alike. Also known as cryptorchidism, an undescended testicle is one that hasn’t moved into its proper position in the scrotum before birth. Typically, only one testicle is affected, but in some cases, both may ... Read More about Undescended testicles: Why prompt referral is key
Our Community
Contributing to every level of care: Our Asian American and Pacific Islander community
People come to Boston Children’s Hospital to receive care from some of the best clinicians in the world. Yet the safe, nurturing environment that greets patients and families is the work of an extensive team. The Environmental Services team, for instance, works tirelessly to ensure every area of the hospital remains clean and welcoming. The ... Read More about Contributing to every level of care: Our Asian American and Pacific Islander community
Research
COVID-19’s devastating toll: An increase in adolescent suicides and mental health crises
The past decade has seen worrisome increases in self-harm, suicidal ideation, and suicide attempts among adolescents. Two new studies from Boston Children’s Hospital show that the situation became even more acute with the onset of COVID-19. Epidemiologist Maimuna Majumder, PhD, and colleagues at the Computational Health Informatics Program (CHIP) at Boston Children’s partnered with public health ... Read More about COVID-19’s devastating toll: An increase in adolescent suicides and mental health crises
Research
Fetal brain imaging predicts neurodevelopment of babies with congenital heart disease
Children with congenital heart disease (CHD) often have neurodevelopmental impairment. Until fairly recently, this was thought to stem from complications of cardiac surgery or reduced oxygen supply to the brain due to the heart defect. Now we know that some babies with CHD have impaired brain development in utero because of low oxygen supply to ... Read More about Fetal brain imaging predicts neurodevelopment of babies with congenital heart disease
Health and Parenting
When athletes have bad days: Tips for athletes and parents
No matter how hard they work, every athlete has bad days. Whether it’s a stumble, fumble, or outright loss, disappointment is a reality of sports. “No one likes the feeling of failing,” says Kelsey Griffith, mental skills specialist at The Micheli Center for Sports Injury Prevention. “But experiencing those emotions is part of the athletic ... Read More about When athletes have bad days: Tips for athletes and parents
Health and Parenting
Shining a light on the SPF gap: Why sun protection is so important for children of color
With summer just around the corner, it’s important to understand the risks that come along with those long, hot days in the sun. It’s also important to recognize some pretty dangerous misconceptions about sun protection — namely that Black children and other children of color don’t need to worry about skin protection and skin cancers. ... Read More about Shining a light on the SPF gap: Why sun protection is so important for children of color
Health and Parenting
The infant formula shortage: Your questions, answered
By now, you’ve likely heard about the current shortage of commercial infant formula: As of today, more than 40 percent of formulas are out of stock across the U.S. The situation has left families scrambling for solutions — and struggling to make sense of a barrage of misinformation online. To get answers, we spoke with ... Read More about The infant formula shortage: Your questions, answered