Archive for heart
Adjusting to sitosterolemia took time, but Justin is now on a healthy path
After Justin Zhao was diagnosed with the rare metabolic disorder sitosterolemia five years ago, the toughest part of treatment was watching his three siblings eat chocolate when he couldn’t. Sitosterolemia is a genetic disease that causes the fatty substances, or lipids, from plant-based foods such as nuts and vegetable oils to build up in the arteries, increasing ... Read More
A new view of heart health: Mutations accumulate in the heart starting in childhood
Why do so many people get heart disease when they get older? We know that factors like high blood pressure or high cholesterol contribute to heart disease risk, but they don’t explain all cases. A first-of-its-kind study from Boston Children’s Hospital offers a new lens on heart health. It shows that the cells of our ... Read More
A new lens on cardiac surgery could help prevent arrhythmia
Sometimes, a change in perspective can lead to a medical breakthrough. A type of microscopy typically used to detect cancer and other diseases has been adapted to reveal the location of unseen conduction tissue around the heart. The Boston Children’s clinician behind this innovation now aims to prove the safety and effectiveness of fiber-optic confocal ... Read More
From South Africa to Boston: Kyleigh’s four-year search for good heart health
Kyleigh Kista had three open-heart surgeries in just the first 18 months of her life. But instead of progressing, her health was rapidly deteriorating by the time she reached 3. Her doctors said there was little else they could do, except make her a candidate for a heart and lung transplant. It was shattering news ... Read More
Getting to the heart of heart muscle function
Every heart muscle cell, or cardiomyocyte, is studded with tiny, intricate structures called dyads. The dyads are like orchestra conductors: They coordinate incoming electrical signals with release of calcium in the muscle, triggering contraction. When dyads work properly, the different segments of heart muscle contract in unison; when they don’t, heartbeats may be too weak ... Read More
Along the way to heart surgery, Liam found a name for his new teddy bear
After a complicated delivery in April 2021, Chelsea Allis had recovered and was finally able to bond with her infant son, Liam. But life became unsettled again only two months later, when a doctor performing a routine checkup on Liam detected a possible heart condition. Then, only a day before seeing a cardiologist to learn ... Read More
Using genetics to glimpse newborns’ future with congenital heart disease
Aside from infections, congenital heart disease (CHD) is the leading cause of infant mortality. Informed by babies she sees in the NICU, Sarah Morton, MD, PhD, attending physician in the Division of Newborn Medicine at Boston Children’s, has devoted her career to understanding CHD’s genetic causes. Her findings are shedding light on what parents and ... Read More
Sudden, unexplained child deaths often have a genetic cause
When a baby or toddler dies without warning, parents often blame themselves. A study at Boston Children’s may provide some insight into sudden, unexplained child deaths and perhaps a measure of closure. It suggests that at least 10 percent of children who die suddenly have an undiagnosed genetic condition that caused or contributed to their ... Read More
A clinical trial aims to reduce complications in life-saving lung and heart treatment
Extracorporeal membrane oxygenation (ECMO) can be lifesaving for critically ill children with severe lung and heart failure who are not responsive to conventional treatments. This approach takes over the work of those vital organs, enabling patients to rest and recover. It transfers blood from the body into a pump-and-oxygenator machine, where blood is oxygenated and carbon ... Read More
Wanting to give back, four heart patients now work as heart pros
They belong to a unique group. As children, they needed surgery to repair congenital heart conditions. Rather than being afraid, they instead were curious about the science behind their treatment. What they learned motivated them to discover more and ultimately pursue careers in medicine. Now healthy adults and working for the Benderson Family Heart Center at Boston ... Read More