Research
Mouse/human model provides new way to study neuroblastoma
Neuroblastoma is a rare childhood cancer affecting about 800 children each year in the United States. Because of its unusual behavior — tumors in infants often disappear spontaneously without treatment while it can be aggressive and fatal in toddlers — studying the disease has been complicated. That may change with a new research tool: a ... Read More about Mouse/human model provides new way to study neuroblastoma
Health and Parenting
What’s it like to have an endoscopy?
If your child has symptoms of gastroesophageal reflux or celiac disease, has been diagnosed with esophageal atresia, or has another condition that affects their upper gastrointestinal (GI) tract, their clinician may recommend an upper endoscopy. In this procedure, the doctor passes a long, thin, flexible tube with a light on the end through your child’s ... Read More about What’s it like to have an endoscopy?
Research
S1P and its receptor: New approaches to cancer?
In 1998, when Timothy Hla, PhD, and his colleagues identified and cloned the receptor for sphingosine-1-phosphate (S1P), it generated a lot of excitement. S1P, a lipid originally discovered in the 1960s, was known to play various roles in the body and in disease. But it wasn’t thought that lipids could have receptors, and it wasn’t ... Read More about S1P and its receptor: New approaches to cancer?
Our Community
Provider Spotlight: Meet Rebecca Stevens
Rebecca Stevens is a pediatric nurse practitioner in the Brain Injury Center at Boston Children’s Hospital. She’s worked at Boston Children’s for almost seven years. What’s your job at Boston Children’s? As a nurse practitioner in the neurology clinic, I mostly see patients who have sustained a concussion or brain injury. I help with ... Read More about Provider Spotlight: Meet Rebecca Stevens
Patient Stories
I never thought this would happen to our son
On June 16, 2019, our 4-year-old son, Evan, fell off a jungle gym at daycare. At first, his daycare provider thought he was fine. He got right up and seemed to recover. She called me and we agreed to watch him to see if there were any changes. A couple hours later, Evan started throwing ... Read More about I never thought this would happen to our son
Patient Stories
Accessing hemophilia care: A tale of two countries
When Miguel and Marco Antonio were born in the Philippines, they had a 50 percent chance of having hemophilia, as two of their uncles had the condition. “We were just crossing our fingers that they’d fall in the other 50 percent,” says Jojo, their father. But when Miguel was taking his first steps as ... Read More about Accessing hemophilia care: A tale of two countries
Research
Long-term hemophilia treatment could lie in patients’ own cells
Children (and adults) with hemophilia are slow to form blood clots, so are at constant risk for uncontrolled bleeding. Even when the skin isn’t broken, a fall or a simple toe stub can become a serious medical issue: internal bleeding cause permanent damage to muscles and joints. While regularly replacing the missing or malfunctioning clotting ... Read More about Long-term hemophilia treatment could lie in patients’ own cells
Research
Child access prevention laws spare gun deaths in children
Child access prevention (CAP) laws are on the books in half of U.S. states. They are meant to protect children from accessing firearms by holding a parent or guardian responsible for the actions or potential actions a child takes with a firearm. New research from Boston Children’s Hospital finds that U.S. states with CAP laws ... Read More about Child access prevention laws spare gun deaths in children
Research
Gliomatosis cerebri: ‘As long as you keep going, you still have hope’
Anna Arabia, the only child of Kathy and Joe Arabia of North Adams, Massachusetts, was 13 when she was diagnosed with gliomatosis cerebri, a rare, rapidly-growing brain cancer. Unlike other tumors, gliomatosis cerebri does not form into lumps; instead it is threadlike, invading multiple lobes of the brain, making it impossible to remove surgically. Anna ... Read More about Gliomatosis cerebri: ‘As long as you keep going, you still have hope’
Patient Stories
Pearson syndrome and the story of William’s cells
William will often ask to hear the “story about his cells.” His mom and dad, Elizabeth and Jeff Reynolds, are always honest. Yet, it is difficult for the 4-year-old to understand words like mitochondrial disease or myelodysplastic syndrome. He also can’t comprehend his parents’ pursuit of a novel treatment for Pearson syndrome, which led them ... Read More about Pearson syndrome and the story of William’s cells