Research
Tuber locations associated with infantile spasms map to a common brain network
About half of all babies with tuberous sclerosis complex (TSC) develop infantile spasms, a type of epilepsy that can have serious long-term neurologic consequences. Infantile spasms occur more often in children who have more brain tubers — groups of cells that do not divide into normal neurons and brain cells — but we haven’t known ... Read More
Our Community
COVID-19 exposed health inequities. These doctors let people know.
What’s a doctor to do when social issues make their patients sick? Traditional medicine can treat disease, but most people don’t realize that problems like racism, poverty, poor housing, and food insecurity can put children and families at risk for a wide range of health problems. Driven by concern that communities of color would experience ... Read More
Health and Parenting
Talking with your child about loss and death
The death toll from COVID-19 has recently surpassed more than 400,000 in the United States and continues to climb. This means that thousands of children have lost someone close to them — a grandparent, an aunt or uncle, a family friend, or even a parent. Some children have lost more than one loved one. Talking ... Read More
Health and Parenting
Chronic headaches in kids: How a psychologist can help your child cope
For many young people, the pain of chronic daily headaches can be compounded by the concern that providers aren’t taking them seriously. Defined as headaches that occur at least 15 days per month for six months or more, chronic daily headaches can be so difficult to manage that some patients may feel that their pain ... Read More
Research
Predicting pediatric seizures with a wristband: Study shows what’s possible
The ability to track seizures has a number of potential benefits: It could allow physicians to better determine optimal dosing and timing of medication, as well as enable timely interventions to help prevent impending seizures. Traditionally, electroencephalography (EEG) and electrocorticography have been used to evaluate and forecast seizures. However, more compact, portable approaches — such ... Read More
Health and Parenting
Answers for parents whose baby is born with brachial plexus injury
Between one and three of every 1,000 babies is born with brachial plexus birth injury. The injury, which may be minor or severe, can impair movement and sensation in a baby’s arm. Because brachial plexus injuries take place during birth, usually without warning, the news leaves many new parents at a loss for what to ... Read More
Research
Specialized T cells protect against the deadliest form of malaria
Each year, there are about 230 million cases of malaria globally. Children under the age of 5 are at highest risk of serious illness and death, accounting for about 265,000 deaths, or nearly 70 percent of all malaria deaths worldwide. Despite significant time and money poured into efforts to develop an effective malaria vaccine, the ... Read More
Health and Parenting
Returning to sports after having COVID-19
Mikey LaCroix, age 23, competes in snowboard cross for the U.S. Snowboard Team. In late 2020, he was diagnosed with COVID-19 and had mild symptoms including a low-grade fever, chills, and loss of smell and taste that lasted about two weeks. Before returning to the slopes after his illness, Mikey had to go through specific ... Read More
Clinical Care
Pharmacogenomics: Nearly 30 percent of children could benefit, study finds
Medications aren’t one-size-fits-all. Genetic differences can affect how patients metabolize drugs, and can sometimes make a beneficial drug ineffective or even toxic. In one infamous case, a 2-year-old boy in Canada died from a codeine dose he received after surgery. A genetic difference caused him to metabolize codeine so quickly that toxic levels of morphine ... Read More
Clinical Care
COVID-19 and surgery: Lessons in safety
When Massachusetts recorded its first COVID-19-positive test result in early March 2020, health officials knew little about the virus. They didn’t know, for instance, how it was transmitted or how to protect patients and clinicians during surgical procedures. In the weeks that followed, Boston Children’s Hospital made several difficult but necessary decisions. We cancelled elective ... Read More