Clinical Care
Two doctors standing next to a grocery cart with a box labeled "healthy food" in the cart.

How Boston Children’s physicians have teamed up to tackle obesity and food insecurity

When nutritious, high-quality food is not easily accessible, families are often left to purchase what is available — usually, highly processed, nutrient-poor food. Children in these households — who also have food insecurity and various socio-economic stressors — face additional barriers and are at risk for developing chronic diseases, such as obesity.  To address such ... Read More about How Boston Children’s physicians have teamed up to tackle obesity and food insecurity
Patient Stories
Teagan, wearing a hearing aid, looks in the mirror.

‘Empowered to be there for Teagan’: New parents learn about hearing loss

Teagan O’Brien is a bright, spunky 4-year-old who loves reading, dancing, and playing outdoors. Her parents, Kim and Donnie, are firefighters who throw themselves into any new situation. Since they adopted Teagan three-and-a-half years ago, they’ve thrown themselves into supporting her with help from her team at Boston Children’s Hospital. Teagan was already a patient ... Read More about ‘Empowered to be there for Teagan’: New parents learn about hearing loss
Research
A health care provider cradles a newborn’s head in their hands at chest height, suggesting a heart.

Mending injured hearts: Lessons from newborns?

When the heart is injured, as in a myocardial infarction, the damaged heart muscle cannot regenerate — instead, scar tissue forms. Cardiomyocytes, the heart muscle cells that generate contractile force, are lost for good. Yet, in mouse models, the hearts of newborns regenerate readily after injury. How are newborn hearts able to recover? What are ... Read More about Mending injured hearts: Lessons from newborns?
Patient Stories
Shannon and Mike holding Luke and Liam.

Finding comfort and answers for twin-twin transfusion syndrome: Shannon’s story

Shannon’s journey through a challenging pregnancy with TTTS (twin-twin transfusion syndrome) was, as she puts it, an emotional rollercoaster. In addition to the usual first-time parent jitters and the unexpected news of twins, Shannon and Mike navigated the emotional ups and downs of the rare pregnancy complication. TTTS put their twins at severe risk of ... Read More about Finding comfort and answers for twin-twin transfusion syndrome: Shannon’s story
Clinical Care
A teen patient in consultation with a health care professional.

Medical care for youth with neurodevelopmental disabilities: A call for change

According to national data, one in six children has a neurodevelopmental disability (NDD) such as autism, intellectual disability, or ADHD. Their medical care is often inadequate, sometimes leaving conditions untreated and neglecting preventive care — with poorer outcomes as the result. Clinicians may not take time to communicate with children, teens, and young adults with ... Read More about Medical care for youth with neurodevelopmental disabilities: A call for change
Health and Parenting
And orthopedic doctor examines a young patient's foot.

Questions to ask about your child’s orthopedic care

Maybe your child has an orthopedic injury and needs surgery, or maybe they need to be treated with a different method. Either way, asking questions can help you understand their doctor’s recommendations and how to prepare for whatever comes next. “Families often find themselves unprepared for their child’s mobility limitations as they heal from surgery ... Read More about Questions to ask about your child’s orthopedic care
Research
Two researchers in lab coats hoist a vaccine syringe, surrounded by B cells and antibodies.

Building better antibodies, curbing autoimmunity: New insights on B cells

When we’re vaccinated or exposed to an infection, our B cells spring into action, churning out antibodies that are increasingly potent, specific, and protective. This happens through an iterative process known as affinity maturation. Two labs at Boston Children’s Hospital have come up with different ways to enhance affinity maturation and help B cells make ... Read More about Building better antibodies, curbing autoimmunity: New insights on B cells
Clinical Care
Eight heart clinicians stand behind a table in a hospital break room.

A surgeon’s last-minute trip to Sri Lanka reduces children’s wait for needed heart repair

Last year, Dr. Christopher Baird got an offer he couldn’t refuse — something that happens often as he travels the world to demonstrate the heart surgery techniques he has learned and developed at Boston Children’s Hospital. At a heart surgery symposium in India, Dr. Baird had just performed a complex type of aortic valve reconstruction ... Read More about A surgeon’s last-minute trip to Sri Lanka reduces children’s wait for needed heart repair
Research
A large intestine with a magnifying glass revealing five different types of intestinal cells.

A journey through the intestine during colitis, cell by cell

Inflammatory bowel disease (IBD), causing devastating abdominal pain, persistent diarrhea, and rectal bleeding, is hard to control with current treatments. Children often experience malnutrition and impaired growth. To get a better handle on IBD, researchers at Boston Children’s Hospital and Brigham and Women’s Hospital decided to eavesdrop on happenings in the colon. In the first ... Read More about A journey through the intestine during colitis, cell by cell
Research
An illustration shows the BRD7 protein moving through two insulin signaling pathways.

BRD7 research points to alternative insulin signaling pathway

Bromodomain-containing protein 7 (BRD7) was initially identified as a tumor suppressor, but further research has shown it has a broader role in other cellular processes, including the remodeling of chromosomes and cell cycle progression. Now, Boston Children’s Division of Endocrinology researchers have discovered another purpose for BRD7: It seems to be involved in an alternative insulin signaling ... Read More about BRD7 research points to alternative insulin signaling pathway