Archive for cardiac research
New findings show risk of bleeding and clotting after COVID-19
A year after COVID-19 was first identified, we have some answers about how to prevent and treat this illness, but there are still many questions. Some of the unknowns include what longer-term effects COVID-19 infection may have on the heart and other systems in the body. One of the complications associated with COVID-19 infection is ... Read More about New findings show risk of bleeding and clotting after COVID-19
The brightest rainbow follows the darkest storm: Our PVS journey
Caroline is our rainbow baby, born after the loss of another child, the light and color arising after a storm passes. A rainbow baby lifts a family in desperate need of lifting. It is a beautiful thing that I hope you never experience. Caroline was born on Dec. 10, 2015. Just three months later, my ... Read More about The brightest rainbow follows the darkest storm: Our PVS journey
Two new approaches to identifying conduction tissue
Conduction cells in the heart are responsible for initiating contraction of the heart muscle. The inability to properly identify the location of conduction tissue in patients with congenital heart defects during heart surgery can lead to post-operative conduction abnormalities such as heart block or conduction delays. This necessitates the need for pacemakers, which leads to ... Read More about Two new approaches to identifying conduction tissue
Coordinated care and research for genetic cardiovascular disorders
Genetic cardiovascular disease in children sometimes comes to light in a crisis — a sudden collapse, sudden breathing difficulty, a sudden death in the family. Or it may be part of a diverse collection of symptoms, mostly having nothing to do with the heart. Sometimes it is picked up incidentally. “From an incidental ECG finding ... Read More about Coordinated care and research for genetic cardiovascular disorders
MIS-C: The tip of an iceberg? Looking at cardiac care for this rare syndrome
In the early days of the COVID-19 outbreak, it seemed that children were far less likely to develop serious problems from the disease than adults. Then in mid-March, hospitals started reporting an unusual inflammatory syndrome in children that seemed to be related to COVID-19, now known as multisystem inflammatory syndrome in children (MIS-C). MIS-C can ... Read More about MIS-C: The tip of an iceberg? Looking at cardiac care for this rare syndrome
Gene therapy reverses heart failure in mouse model of Barth syndrome
Barth syndrome is a rare metabolic disease caused by mutation of a gene called tafazzin or TAZ. It can cause life-threatening heart failure and also weakens the skeletal muscles, undercuts the immune response, and impairs overall growth. Because Barth syndrome is X-linked, it almost always occurs in boys. There is no cure or specific treatment. ... Read More about Gene therapy reverses heart failure in mouse model of Barth syndrome
Someday, this prosthetic heart valve might be the only one a child needs
More than 330,000 children worldwide are born with a heart valve defect, and millions of others develop rheumatic heart disease requiring early valve replacement. Current prosthetic heart valves are fixed in size, so typically need to be replaced every few years as a child grows. For children receiving their first replacement before age 2, that ... Read More about Someday, this prosthetic heart valve might be the only one a child needs
PICU Up! Program aims to increase mobility in ICUs
For decades, clinicians believed the most appropriate care for critically ill pediatric patients was sedation and rest. But in recent years, the tides have changed. Studies in adults have shown that sedation and immobility lead to increased mortality and morbidity, longer stays in the intensive care unit (ICU), increased risk of ICU delirium, and a ... Read More about PICU Up! Program aims to increase mobility in ICUs
Healing hearts under a watchful eye
Cardiac surgery is performed using visual landmarks inside the heart. There are specialized conduction tissues that run underneath the surface, which are important for the heart’s rhythmic beating. Cardiac surgeons operate with these landmarks in mind to avoid injury to conduction tissue, but locating these tissues can be challenging. Fiberoptic confocal microscopy technology inside the ... Read More about Healing hearts under a watchful eye
Tissue models and a gene therapy for a deadly heart arrhythmia
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a leading cause of sudden death from cardiac arrest in children and young adults. Marked by racing, irregular heartbeats, the inherited arrhythmia is typically silent until a child suddenly collapses and faints, at an average age of 12. The trigger is an adrenaline surge, caused by exercise or emotional ... Read More about Tissue models and a gene therapy for a deadly heart arrhythmia