Research
Specialized T cells protect against the deadliest form of malaria
Each year, there are about 230 million cases of malaria globally. Children under the age of 5 are at highest risk of serious illness and death, accounting for about 265,000 deaths, or nearly 70 percent of all malaria deaths worldwide. Despite significant time and money poured into efforts to develop an effective malaria vaccine, the ... Read More about Specialized T cells protect against the deadliest form of malaria
Health and Parenting
Returning to sports after having COVID-19
Mikey LaCroix, age 23, competes in snowboard cross for the U.S. Snowboard Team. In late 2020, he was diagnosed with COVID-19 and had mild symptoms including a low-grade fever, chills, and loss of smell and taste that lasted about two weeks. Before returning to the slopes after his illness, Mikey had to go through specific ... Read More about Returning to sports after having COVID-19
Clinical Care
Pharmacogenomics: Nearly 30 percent of children could benefit, study finds
Medications aren’t one-size-fits-all. Genetic differences can affect how patients metabolize drugs, and can sometimes make a beneficial drug ineffective or even toxic. In one infamous case, a 2-year-old boy in Canada died from a codeine dose he received after surgery. A genetic difference caused him to metabolize codeine so quickly that toxic levels of morphine ... Read More about Pharmacogenomics: Nearly 30 percent of children could benefit, study finds
Clinical Care
COVID-19 and surgery: Lessons in safety
When Massachusetts recorded its first COVID-19-positive test result in early March 2020, health officials knew little about the virus. They didn’t know, for instance, how it was transmitted or how to protect patients and clinicians during surgical procedures. In the weeks that followed, Boston Children’s Hospital made several difficult but necessary decisions. We cancelled elective ... Read More about COVID-19 and surgery: Lessons in safety
Health and Parenting
Facing up to masks: Six reasons to stay the course
It’s now been almost a year since many businesses shuttered, schools closed, and Zoom calls became a way of life for many of us. Among the changes: face masks, designed to help prevent the spread the virus that causes COVID-19. If you’re experiencing so-called mask exhaustion, you’re not alone. One recent survey found that half ... Read More about Facing up to masks: Six reasons to stay the course
Innovative new shunt delivery system holds promise for treatment of fetal urinary tract obstruction
Urinary tract obstruction that occurs in utero can have serious consequences for the fetus. Such obstructions can block the flow of fetal urine, which makes up amniotic fluid. Without adequate levels of amniotic fluid, a fetus may not develop properly, especially in terms of the fetal lungs. Fetal urinary tract obstructions can range from mild ... Read More about Innovative new shunt delivery system holds promise for treatment of fetal urinary tract obstruction
Patient Stories
Finally heard: How finding a doctor who listened helped change Carter’s life
In some ways, Carter Sousa is like any other 13-year-old: He’s obsessed with videos, loves animals, and enjoys hanging out with his friends. But for much of his childhood, Carter and his parents found themselves struggling with a frustrating and embarrassing problem that seemed to have no clear solution. Soon after he was born, Carter ... Read More about Finally heard: How finding a doctor who listened helped change Carter’s life
Health and Parenting
Eight tips to help you make it through the winter
It’s officially 2021 and we have two approved vaccines for COVID-19 that are rolling out across the country. While this is great news, the reality is that we’re still facing a few more months of social distancing before we’re able to return to any type of “normal” lifestyle. And in the chill and darkness of ... Read More about Eight tips to help you make it through the winter
Health and Parenting
The COVID-19 vaccine for kids: When will children be vaccinated?
In late 2020, the U.S. Food and Drug Administration (FDA) gave emergency use authorization to two COVID-19 vaccines — one from Pfizer/BioNTech, the other from Moderna. Other vaccines are expected to be authorized soon. Currently the Pfizer vaccine can be given to people ages 16 years and older; Moderna’s is for use in those 18 ... Read More about The COVID-19 vaccine for kids: When will children be vaccinated?
Research
‘Mosaic’ gene mutations could explain some cases of autism
The causes of autism remain mysterious. Scientists have linked autism spectrum disorder to a long list of genes, but most children with autism have no known explanation. Two new studies add to the picture, implicating mutations that affect only a fraction of a child’s cells. Called mosaic mutations, they open a new avenue for research ... Read More about ‘Mosaic’ gene mutations could explain some cases of autism