Research
MEx cells budding off MSC cells

Therapy developed at Boston Children’s stops preeclampsia before it starts

Preeclampsia occurs in about 3 to 5 percent of all pregnancies. Characterized by very high maternal blood pressure, it can lead to serious, sometimes fatal, complications in both mother and baby. In severe cases, early delivery is often the only effective treatment, usually before the baby’s lungs are fully developed. Researchers within the Division of ... Read More about Therapy developed at Boston Children’s stops preeclampsia before it starts
Clinical Care
GVHD prevention

Arthritis drug reduces rates of acute graft-vs-host disease after bone marrow transplant

The immune-suppressing drug abatacept, currently used for rheumatoid arthritis, could make bone marrow transplant safer, report researchers at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. The phase 2 randomized, multi-center clinical trial, the largest to date, appears in the Journal of Clinical Oncology. Abatacept (brand name ORENCIA) reduced rates of severe, acute graft-versus-host disease ... Read More about Arthritis drug reduces rates of acute graft-vs-host disease after bone marrow transplant
Health and Parenting
graphic of SARS-CoV-2 virus 'morphing' into a new virus

The new COVID-19 virus variant: What you need to know

You’ve probably seen news reports about B.1.1.7, a newly discovered version of the SARS-CoV-2 virus that causes COVID-19. Now found in several countries, including the U.S., B.1.1.7 is quickly spreading around the world. Although B.1.1.7 seems to be more contagious, it doesn’t appear to lead to more serious illness. What else do we know about ... Read More about The new COVID-19 virus variant: What you need to know
Health and Parenting
A mother and her child give each other a high five as they prepare food in the kitchen

Is it “good” or “bad” for your child? Removing morality from eating

Teaching our children to eat well is not a simple task — but perhaps that’s because we are looking at it from the wrong angle. Often, we focus on statistics about obesity or eating disorders rather than fostering a positive relationship with food. However, it’s crucial that families understand the seriousness surrounding disordered eating so ... Read More about Is it “good” or “bad” for your child? Removing morality from eating
Patient Stories
Charlee, who had neuroblastoma, poses in front of a door.

Charlee: Bouncing back after neuroblastoma treatment

Call it mother’s intuition, but leading up to her daughter’s cancer diagnosis, Erica Jensen knew something wasn’t right. At just 10 months, Charlee had started walking, and since taking her first steps the excited toddler was constantly exploring the world around her. Then, at around 15 months, something changed. It wasn’t obvious at first — ... Read More about Charlee: Bouncing back after neuroblastoma treatment
Clinical Care
Mila, the first patient to be treated with an n of 1 drug made just for her

Made-to-order therapies get a boost with new FDA guidelines

Ed. note: Mila passed away in February, 2021, at age 10. The Mila’s Miracle Foundation continues to work to pave a pathway for personalized treatments. Science-based treatments for rare genetic diseases have burgeoned in the past decade. That includes diseases so rare they affect just a handful of patients — or in some cases, just ... Read More about Made-to-order therapies get a boost with new FDA guidelines
Research
photo of a smiling teenager

Hip reconstruction in complex patients: Predicting complications

Neuromuscular hip dysplasia and progressive spastic hip displacement are among the most common orthopedic concerns in non-ambulatory children with cerebral palsy (CP), leading to pain, decreased function, and impaired quality of life. While hip reconstruction surgery can improve quality of life in these children, it can be associated with acute post-operative pain, medical complications, and ... Read More about Hip reconstruction in complex patients: Predicting complications
Health and Parenting
gloved hand holding vaccine bottle and syringe

COVID-19 vaccines: Do you know myth from fact?

Two COVID-19 vaccines — from Pfizer/BioNTtech and Moderna  — have received emergency use authorization in the United States by the U.S. Food and Drug Administration (FDA). Many more are in various stages of development around the world. Several of these are in the final stage of clinical trials and could be submitted for formal authorization ... Read More about COVID-19 vaccines: Do you know myth from fact?
Clinical Care
graphic of blood sugar monitor superimposed over apples and blood drop

Low-carb diets for diabetes: Rediscovering centuries-old wisdom

This year represents the 100th anniversary of the discovery of insulin, a hormone that regulates the amount of glucose, or sugar, in the blood. While insulin medications have literally been life-savers for many kids and adults with diabetes, diets that help keep blood sugar levels steady are often overlooked for controlling diabetes. These diets, often ... Read More about Low-carb diets for diabetes: Rediscovering centuries-old wisdom