Made-to-order therapies get a boost with new FDA guidelines
Science-based treatments for rare genetic diseases have burgeoned in the past decade. That includes diseases so rare they affect just a handful of patients — or in some cases, just one. In 2017, researchers at Boston Children’s Hospital made history, creating a customized drug for a girl named Mila with Batten disease. The drug blocked ... Read More
Low-carb diets for diabetes: Rediscovering centuries-old wisdom
This year represents the 100th anniversary of the discovery of insulin, a hormone that regulates the amount of glucose, or sugar, in the blood. While insulin medications have literally been life-savers for many kids and adults with diabetes, diets that help keep blood sugar levels steady are often overlooked for controlling diabetes. These diets, often ... Read More
2020, the year COVID-19 tuned us into science: Part 3
Since the arrival of a new, unknown, dangerous virus in January, we entered the realm of COVID-19 science. Part 1 and Part 2 of this series recapped what we learned about how the virus spreads, how to test for it and treat it, and how COVID-19 plays out in children. This month, vaccines began to be ... Read More
2020, the year COVID-19 tuned us into science: Part 2
Thanks — or no thanks — to COVID-19, 2020 has been a year in which science became a household topic of discussion. Our last post recounted what we collectively learned in the spring: what COVID-19 is, who is at risk, how to test for it. As the year unfolded, there were new lessons to be learned. ... Read More
2020, the year COVID-19 tuned us into science: Part 1
On January 9, the World Health Organization announced a mysterious pneumonia in Wuhan, China. Few people knew it was the threat infectious disease experts had feared for decades: a fast-spreading, potentially deadly new virus with no known cure. As the first images of critically ill patients came out of China and Italy, we watched as ... Read More
New health care data-sharing rule, coming in 2022, has its roots at Boston Children’s Hospital
Are you sick of health care systems not communicating with each other? Do you wish you could access more of your medical information — or your patients’ information — online? Do you ever wonder whether a health pattern you see is part of a larger trend? Two key developments have advanced the vision of seamless, ... Read More
After decades of evolution, gene therapy arrives
As early as the 1960s, scientists speculated that DNA sequences could be introduced into patients’ cells to cure genetic disorders. In the early 1980s, David Williams, MD, and David Nathan, MD, at Boston Children’s Hospital published the first paper showing one could use a virus to insert genes into blood-forming stem cells. In 2003, the ... Read More
In-hospital telehealth: Care innovation during the COVID-19 pandemic
The quick response, or QR, code — that square barcode symbol used by smartphone apps to link users with specific information — became an unexpected but essential tool for patient care at Boston Children’s Hospital in early spring. When the first patients with COVID-19 arrived, it quickly became clear that health care providers needed safer ... Read More
Treating chronic pain virtually: A telehealth success story
When the COVID-19 pandemic forced shutdowns in March 2020, many clinicians found themselves faced with a whole new challenge: conducting much of patient care from their computers. Although telehealth was already a part of some physicians’ practices, others have had to learn how to adapt existing clinical skills to virtual platforms. But there have been ... Read More
At the forefront of kidney stone removal: Innovative approaches transform patient care
No longer considered just an adult problem, kidney stones increasingly affect children as well. The majority of children who cannot pass stones on their own can be treated with minimally invasive approaches such as extracorporeal shock wave lithotripsy, ureteroscopy, percutaneous nephrolithotomy, laparoscopic and robotic approaches and, rarely, open surgery. Now, two recent innovations provide additional ... Read More