Archive for history
After decades of evolution, gene therapy arrives
As early as the 1960s, scientists speculated that DNA sequences could be introduced into patients’ cells to cure genetic disorders. In the early 1980s, David Williams, MD, and David Nathan, MD, at Boston Children’s Hospital published the first paper showing one could use a virus to insert genes into blood-forming stem cells. In 2003, the ... Read More
The polio outbreak of 1955: Lessons from an epidemic
“This is going to be a tough year.” Claire McCarthy was a young physical therapist in early March 1955 when orthopedic surgeon Dr. David Grice, made this observation. At the time, Boston Children’s Hospital was the receiving center for adults and children with polio in New England. The hospital typically saw an upsurge in cases ... Read More
Culture shock: Why poliovirus had to live before it could die
Today, stories of polio may seem like echoes from far-away history to those born after 1979, the year that polio was eradicated in the U.S. Since then, it has been customary for children to receive four doses of the polio vaccine to protect them from ever contracting the terrifying disease also known as “infantile paralysis.” Polio, however, still afflicts people in ... Read More