Patient Stories
Congenital scoliosis: Maria’s story
Growing up in a big family helped. When Maria Dupuis came home from the hospital after surgery to correct her scoliosis, her sisters played Subway Surfer with her and her brothers braided her hair. Having so many siblings around to play with probably motivated her to get up and start walking sooner. And when other ... Read More about Congenital scoliosis: Maria’s story
Research
Protecting against HIV by tricking the immune system
In making an HIV vaccine, a major goal is to stimulate production of broadly neutralizing antibodies that can fight multiple strains of the frequently changing virus. To date, experimental HIV vaccines haven’t been able to induce these kinds of antibodies. In fact, the immune system actively stops their production, seeing them as a threat. Another ... Read More about Protecting against HIV by tricking the immune system
Health and Parenting
Testicular problems in boys: When is surgery necessary?
Testicular problems can be a source of alarm for parents of boys, but they’re actually quite common. Here, Dr. Erin McNamara, a pediatric urologist in the Department of Urology at Boston Children’s Hospital, explains testicular abnormalities and shares when to consider surgery. Undescended testicles Before a baby boy is born, his testicles form in his ... Read More about Testicular problems in boys: When is surgery necessary?
Research
A potential Diamond-Blackfan anemia treatment swims into view
Zebrafish, besides being popular in aquariums, make good stand-ins for studying human diseases. They share about 70 percent of their genes with humans, and can be studied at a mass scale, enabling scientists to test hundreds, even thousands of drugs at a time simply by adding the drug to their water. One such test came ... Read More about A potential Diamond-Blackfan anemia treatment swims into view
Clinical Care
When athletes push too hard: How to screen and when to refer
With the rise in the number and competitiveness of female athletes, overtraining has become a serious health risk for many young women. Whether it comes from a coach, parent, teammate, or the athlete herself, the pressure to perform drives many young athletes to practice unsafe behaviors in an effort to boost performance. Instead of building ... Read More about When athletes push too hard: How to screen and when to refer
Clinical Care
A big step toward curbing graft-vs.-host disease after bone marrow transplant
A drug used for rheumatoid arthritis has moved a step closer to FDA approval for a desperately needed new use. The drug, abatacept, has gained FDA Breakthrough Therapy Designation for preventing acute, severe graft-versus-host disease (GVHD) in patients receiving bone marrow transplants. That could help fast-track the drug to the clinic. “If we are lucky ... Read More about A big step toward curbing graft-vs.-host disease after bone marrow transplant
Patient Stories
BACH Program: Heart care for patients of all ages
At 73, Fran Sansalone might not seem like a typical Boston Children’s Hospital patient. But she’s one of a growing number of adults who visit the Heart Center regularly. Fran has been a patient in the Boston Adult Congenital Heart (BACH) Program for the past 18 years. Like other adults born with a congenital heart ... Read More about BACH Program: Heart care for patients of all ages
Research
Identifying specific markers in blood may improve diagnosis of IBD in children
New research may lead to improved methods to diagnose inflammatory bowel disease (IBD) in children. This could be especially beneficial for those experiencing malnutrition and impaired growth as a result of this condition, since it could shorten their wait time to access needed treatments. Identifying a common gene in blood and colon tissue samples Scientists from Boston ... Read More about Identifying specific markers in blood may improve diagnosis of IBD in children
Research
A nimbler way to track alcohol use: mining Twitter and Google searches
Large, survey-based studies are a slow, expensive way to collect rigorous public health data. New research, focusing on alcohol use, shows that mining Twitter and online searches could enable public health professionals to get immediate, localized insights, spot emerging trends, and even measure the effects of interventions. “Online user-generated data are fluid and nimble — ... Read More about A nimbler way to track alcohol use: mining Twitter and Google searches
Research
Internal brain timers linked with motivation and behavior
Time can be measured in many ways: a watch, a sundial, or the body’s natural circadian rhythms. But what about the sexual behavior of a fruit fly? “If you ask a bunch of scientists whether animals can keep time, many would say they cannot, that things happen over time—but time itself is not measured,” says ... Read More about Internal brain timers linked with motivation and behavior