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An adolescent girl doubled over in despair, to illustrate concept of suicidality.

COVID-19’s devastating toll: An increase in adolescent suicides and mental health crises

Clinical, Research
The past decade has seen worrisome increases in self-harm, suicidal ideation, and suicide attempts among adolescents. Two new studies from Boston Children’s Hospital show that the situation became even more acute with the onset of COVID-19. Epidemiologist Maimuna Majumder, PhD, and colleagues at the Computational Health Informatics Program (CHIP) at Boston Children’s partnered with public health ... Read More about COVID-19’s devastating toll: An increase in adolescent suicides and mental health crises
Tagged: adolescent medicine, advocacy, coronavirus, mental health, research, suicide
Illustration of a pregnant mother about to have an MRI scan, with a drawing of her fetus projected over her and highlighting the baby’s brain.

Fetal brain imaging predicts neurodevelopment of babies with congenital heart disease

Clinical, Research
Children with congenital heart disease (CHD) often have neurodevelopmental impairment. Until fairly recently, this was thought to stem from complications of cardiac surgery or reduced oxygen supply to the brain due to the heart defect. Now we know that some babies with CHD have impaired brain development in utero because of low oxygen supply to ... Read More about Fetal brain imaging predicts neurodevelopment of babies with congenital heart disease
Tagged: cardiac neurodevelopment, congenital heart defect, fetal cardiology, fetal medicine, imaging, neurology
A women's head with stylized lightning bolts in the prefrontal cortex and hippocampus areas of her brain, indicating Alzheimer's mutations.

A new angle on the cause of Alzheimer’s disease: Accumulating brain mutations

Basic/Translational, Research
Alzheimer’s disease is marked by a loss of functional neurons in the brain. But what causes this loss? A new study reveals that people with Alzheimer’s have an abundance of newly acquired mutations in their neurons — more than people of the same age without Alzheimer’s, and enough to disable genes important to brain function. ... Read More about A new angle on the cause of Alzheimer’s disease: Accumulating brain mutations
Tagged: alzheimers disease, genetics and genomics, neuroinflammation, neuroscience
Nurse practitioner Katie Roy, one of Boston Children’s nurses celebrated during Nurses Week 2022.

Nurses Week 2022: Patients at high risk for adverse events related to sepsis

Research
Boston Children’s commitment to exceptional patient care and the best possible outcomes inspires innovation and growth. Both the hospital and its nursing leadership encourage professional development of employees through a variety of research and educational programs. The professional practice of Katie Roy, DNP, RN, CPNP-AC, FNP-BC, nurse practitioner, Medical-Surgical Intensive Care Unit (MSICU), provides a ... Read More about Nurses Week 2022: Patients at high risk for adverse events related to sepsis
Tagged: icu, nursing, sepsis
An illustration of a catheter in the center connects an image of doctors on the left with one of an EKG line of a beating heart.

“Seeing” the unseen: A way to pinpoint elusive cardiac conduction tissue

Clinical, Research
When patients with congenital heart issues have an operation, surgeons have to proceed with an “eye of faith” as they work around conduction tissue — a network of cells and electrical signals that control the beating of a heart. Not visible to the naked eye, conduction systems vary person to person, but they’re particularly difficult ... Read More about “Seeing” the unseen: A way to pinpoint elusive cardiac conduction tissue
Tagged: arrhythmia, biventricular repair, cardiac research, cardiac surgery, electrophysiology
circles to represent liver cancer cells in the crosshairs

Immunotherapy for kids: An option for childhood liver cancer?

Research
You may have seen ads for immunotherapy drugs, or even know someone whose cancer has been treated with them. These medications, which use a patient’s own immune system to help fight cancer, are increasingly popular for treating solid tumors in adults. However, immunotherapy has been less successful in treating cancer in kids. The reason for ... Read More about Immunotherapy for kids: An option for childhood liver cancer?
Tagged: cancer, immunotherapy, liver disease
An illustration of the brain with fluid-filled ventricles at its center.

Beyond fluid buildup: Rethinking congenital hydrocephalus

Basic/Translational, Research
Hydrocephalus is classically seen as a plumbing problem, the result of too much cerebrospinal fluid (CSF) in the brain or dysregulation of fluid flow. It is usually treated with shunts to drain the CSF, or with ETV/CPC, which makes a small hole to drain the CSF and burns off the choroid plexus tissue that produces ... Read More about Beyond fluid buildup: Rethinking congenital hydrocephalus
Tagged: brain malformation, genetics and genomics, hydrocephalus, neurology, neuroscience, neurosurgery
illustration of doctors looking at charts and graphs

Drawing on data to revolutionize pediatric urology

Research
At first blush, data analytics — sifting through raw data to discover patterns and draw conclusions from them — seems far afield from the practice of pediatric urology. One discipline involves crunching numbers at a computer, while the other involves caring for patients in the clinic or operating room (OR). But for members of Boston ... Read More about Drawing on data to revolutionize pediatric urology
Tagged: artificial intelligence, urinary tract infection, urology
Alt text: Illustration of a teen and his mother beside their car at night, apparently homeless

When a critically ill child is homeless

Clinical Care, Research
On a single night in 2020, roughly 172,000 in families with children and 34,000 unaccompanied youth under age 25 were homeless, according to government figures. Many more families are housing insecure amid skyrocketing rents.   A large body of research finds that both situations put children at increased risk for health problems. Parents may have ... Read More about When a critically ill child is homeless
Tagged: complex care, critical care, health equity, poverty
Illustration of monocytes in the bloodstream that appear to be on fire, igniting COVID-19 inflammation

How COVID-19 triggers massive inflammation

Basic/Translational, Research
Why do some people with COVID-19 develop severe inflammation, leading to respiratory distress and damage to multiple organs? A new study in the journal Nature provides an explanation: the SARS-CoV-2 virus infects and kills critical immune cells in the blood and lungs, which set off powerful alarm bells as they die. Judy Lieberman, MD, PhD, ... Read More about How COVID-19 triggers massive inflammation
Tagged: cellular and molecular medicine, coronavirus, immunology, infectious diseases

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