Archive for hydrocephalus
On her own terms: Robot-assisted procedure gives Sage more independence
At 19, Sage Nault has had multiple surgeries, aimed at addressing challenges related to myelomeningocele, the most severe form of spina bifida. But it’s her most recent operation that might have the greatest impact on her quality of life. Known as a Mitrofanoff appendicovesicostomy and a Malone antegrade continence enema (MACE), the combined procedure has ... Read More
Could gene therapy relieve post-hemorrhagic hydrocephalus?
Premature infants, especially very low birthweight babies, are at risk for intraventricular hemorrhage. A frequent complication of these brain bleeds is hydrocephalus, an accumulation of cerebrospinal fluid (CSF) in the brain ventricles that can gravely disrupt brain development. If hydrocephalus develops, a child may need shunt operations throughout life to manage the fluid buildup. Could ... Read More
Beyond fluid buildup: Rethinking congenital hydrocephalus
Hydrocephalus is classically seen as a plumbing problem, the result of too much cerebrospinal fluid (CSF) in the brain or dysregulation of fluid flow. It is usually treated with shunts to drain the CSF, or with ETV/CPC, which makes a small hole to drain the CSF and burns off the choroid plexus tissue that produces ... Read More
Exploring an unsung part of the brain: the choroid plexus
If you’ve never heard of the choroid plexus, you’re not alone. In fact, few neuroscientists know much about this part of the brain. In the words of the late comedian Rodney Dangerfield, the choroid plexus “don’t get no respect.” But that’s beginning to change, thanks in part to Maria Lehtinen, PhD, who has made the ... Read More
Care for stroke lets Matty just be a kid
Most adults might encourage kids to behave themselves, but Matthew Marino’s doctor wants to help him make mischief. “He told us that he loves when kids cause trouble and that he wants to help Matt cause trouble, too,” says his mother, Maura, of Dr. David Fogelman, a physiatrist in the Stroke and Cerebrovascular Center at ... Read More
Do antibiotic-impregnated shunts reduce infection in hydrocephalus?
Every year, nearly 400,000 children worldwide develop hydrocephalus, in which excess fluid accumulates in the brain. Many of these children have shunts placed to allow this fluid to drain. Antibiotic-impregnated shunts are widely championed as the best choice, but a recent study calls their necessity into question. The study, published in the Journal of Neurosurgery ... Read More
Detecting shunt failure in hydrocephalus without imaging or surgery: ShuntCheck
Antonio Venus-Reeve, 14, had his first shunt surgery for hydrocephalus when he was 2½ months old. Born at 25 weeks’ gestation, weighing less than two pounds, he had a serious brain bleed seven days later. As Antonio’s head began to swell with excess fluid, neurologists at Boston Children’s Hospital told his mother, Joanne Venus-Williams, that ... Read More
The birth of ShuntCheck: Family, love, passion, death—and ice
The year was 2002, and 10-year-old Spencer Neff was a spunky boy with hydrocephalus, a buildup of cerebrospinal fluid inside his brain. A surgically implanted shunt – a tube to drain the fluid – was in place. Like all children with shunts, he was at risk for having the shunt plug up and malfunction, and ... Read More