Patient Stories
Bone cancer surgery: A difficult choice
Nolan and Natasha might never have met if they hadn’t been diagnosed with bone cancer. Nolan, 13, is a natural athlete who lives in Maine. Natasha, 11, lives in Rhode Island and loves music and theater. As kids go, the two are pretty different — except for their osteosarcoma diagnoses and the surgery to remove ... Read More about Bone cancer surgery: A difficult choice
Clinical Care
A global view of rheumatic disease during COVID-19
COVID-19 is bringing new challenges to many people with underlying rheumatic disease who already are immunocompromised by the very nature of their illnesses or the medications used to treat them. To help manage those uncertainties in the current climate, Boston Children’s Hospital is participating in two surveys: one collecting information from rheumatologists, the other directly ... Read More about A global view of rheumatic disease during COVID-19
Clinical Care
Trial tests dornase alfa, a cystic fibrosis drug, for severe COVID pneumonia
Boston Children’s Hospital and Brigham and Women’s Hospital will soon begin testing an existing drug, dornase alfa, in patients with severe COVID-19 pneumonia and respiratory failure. The randomized, controlled clinical trial aims to enroll 60 adults and children over age 3 who require mechanical ventilation. Key takeaways:· A randomized trial is testing whether a cystic ... Read More about Trial tests dornase alfa, a cystic fibrosis drug, for severe COVID pneumonia
Research
A master regulator of kidney health?
End-stage kidney disease often begins with injury to podocytes. These highly specialized cells are a critical part of the glomeruli, clusters of capillaries that serve as the filtration units in our kidneys’ tightly-packed nephrons. As their name suggests, podocytes extend tiny foot processes to intermingle with the capillaries and filter the blood, maintaining the proper ... Read More about A master regulator of kidney health?
Research
Nurses, COVID-19, and PTSD: When it hurts to care
When Boston Children’s Michelle Schuster, MSN, RN, CPHON, inpatient oncology/hematology staff nurse and Patricia Dwyer, PhD, RN, CNOR, nurse scientist, set out to study post-traumatic stress disorder (PTSD) in nurses, they weren’t thinking about COVID-19. The two had been studying PTSD in nurses for almost two years when the pandemic hit. Key takeaways· PTSD is ... Read More about Nurses, COVID-19, and PTSD: When it hurts to care
Health and Parenting
When your baby has clubfoot: Answers for expecting parents
Treatment for clubfoot usually begins within a few weeks of a child’s birth. With prenatal ultrasound, parents often learn about clubfoot weeks or months before their child’s arrival. Below, Dr. Collin May of the Lower Extremity Program in Boston Children’s Orthopedic Center answers questions about how meeting with an orthopedic specialist can ease expecting parents’ ... Read More about When your baby has clubfoot: Answers for expecting parents
Patient Stories
Isolde’s story: A concussion leads to 3PD
When Isolde Edson was injured in the fall of 2018, during the last junior varsity soccer game of the season, she had no idea she’d still be dealing with the repercussions nearly two years later. “During a home game at the end of the season, I jumped up to kick the ball, and a girl ... Read More about Isolde’s story: A concussion leads to 3PD
Research
Capturing SARS-CoV-2’s shape-shifting spike protein
The rod-like spike proteins on the surface of SARS CoV-2 are the tip of the spear of the COVID-19 pandemic. The spikes bind to human cells via the ACE2 receptor and then dramatically change shape. They jack-knife, folding in on themselves to fuse their own membrane with the membrane of our cells. And that opens ... Read More about Capturing SARS-CoV-2’s shape-shifting spike protein
Clinical Care
Utilizing engineering tools from the aerospace industry to repair hearts
When an 18-year-old patient from North Carolina recently presented at Boston Children’s Heart Center with an enlarged right atrium that made the flow through his Fontan circulation very inefficient, David Hoganson, MD, decided to utilize a new set of tools borrowed from the aerospace industry. “We have been collaborating with Dassault Systemes for over a ... Read More about Utilizing engineering tools from the aerospace industry to repair hearts
Health and Parenting
Should you hire a babysitter during COVID-19? Six tips to consider
If you’ll be going back to work outside of the home, you may wonder if it’s safe to hire a babysitter during COVID-19. While this decision is a very personal one, for some families it can be an appealing alternative to using a daycare center— as long as you can find a caregiver you trust ... Read More about Should you hire a babysitter during COVID-19? Six tips to consider