Research
A boy gazing out a window

Firearm suicides in children and youth: A state-by-state look

At a time when mental health problems are skyrocketing, a new study provides one of the most comprehensive state-by-state accountings to date of firearm suicides in children and youth. The findings, published in JAMA Pediatrics, are eye-opening — but could also help in crafting interventions. Lois Lee, MD, MPH, in the Division of Emergency Medicine ... Read More about Firearm suicides in children and youth: A state-by-state look
Research
A masked researcher at the lab bench pipetting, to illustrate idea of genome sequencing.

Making genome sequencing a first-line test in rare disease

Children with rare diseases often undergo years of medical visits and genetic testing before they get a diagnosis. Over the past few years, clinics have started to embrace exome sequencing as a first genetic test, skipping time-consuming testing of individual genes and gene panels and getting to a diagnosis faster. But exome sequencing doesn’t always ... Read More about Making genome sequencing a first-line test in rare disease
Research
A dendritic cell in the crosshairs.

Boosting vaccines for the elderly with ‘hyperactivators’

As we age our immune systems start to flag, leaving us more susceptible to cancer and infections — and less responsive to vaccines and cancer immunotherapies. Going to the heart of the problem, Jonathan Kagan, PhD, a researcher in immunology at Boston Children’s Hospital, has identified a way to rejuvenate the elderly immune system. His ... Read More about Boosting vaccines for the elderly with ‘hyperactivators’
Research
Intestines and a brain, with a feedback loop between them, highlighting the concept of the microbiome influencing OCD.

The gut-brain connection: A new approach to OCD and tic disorders?

It’s natural for young children to use routines to help them navigate the world and for older children and teens to zero in on interests and hobbies. But if they veer into disruptive, unwanted obsessions or thoughts or the need to perform compulsive rituals, they may have obsessive-compulsive disorder (OCD). We know that OCD is ... Read More about The gut-brain connection: A new approach to OCD and tic disorders?
Patient Stories
An aging black-and-white photo of Bruce Chansky

Ted Williams, chocolate milkshakes, and a pioneering heart team: What Bruce remembers about his heart surgery 65 years later

Bruce Chansky was the star of his neighborhood after he had heart surgery at Boston Children’s. It was 1959, a time when a child having heart surgery wasn’t common — it was newsworthy. Eleven-year-old Bruce was featured in his hometown newspaper, which only furthered his celebrity in Beverly, Massachusetts. Friends, neighbors, and strangers all wanted ... Read More about Ted Williams, chocolate milkshakes, and a pioneering heart team: What Bruce remembers about his heart surgery 65 years later
Research
Amar Majmundar and Nina Mann on a bridge connecting Boston Children's Hospital with a parking garage.

Two rising stars in kidney genetics: Nina Mann and Amar Majmundar

A healthy, functional kidney must maintain a delicate balance of water, nutrients, and electrolytes so it can properly filter the blood and produce urine. That often makes caring for patients with kidney disease an exercise in chemistry and mathematics — an aspect of nephrology that attracted two young physician-scientists. Coming from different paths, Nina Mann, ... Read More about Two rising stars in kidney genetics: Nina Mann and Amar Majmundar
Patient Stories
Freddy and Alexandra holding baby Ana Sofia.

For Ana Sofia: How one mom found prenatal care for fetal pleural effusion

Alexandra is the first to admit she asks a lot of questions and needs to know details. “I’m curious about everything, and I want to know everything,” she says. “I do my research. I’m a pretty resourceful person.” It’s something she says can be off-putting to some people, but it’s also what saved her daughter’s ... Read More about For Ana Sofia: How one mom found prenatal care for fetal pleural effusion
Health and Parenting
A child with a cochlear implant does language exercises with an audiologist.

Are cochlear implants an option for my child?

By providing access to sound, cochlear implants have made it possible for children with severe to profound hearing loss to communicate through speech. The devices transmit signals from external processors to the brain via units implanted underneath the skin and small wires connected to the inner ear. “Cochlear implants can be life changing for a ... Read More about Are cochlear implants an option for my child?
Research
A person with pain hotspots with an immune cell and neuron in dialog.

A deeper understanding of inflammatory pain could reveal new solutions

Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are the main go-to for inflammatory pain caused by wounds, infection, sunburn, arthritis, and other triggers. NSAIDs work pretty well, but chronic use can cause side effects, and they aren’t equally effective for all sources of pain. Could we identify a more effective, safer analgesic that doesn’t involve ... Read More about A deeper understanding of inflammatory pain could reveal new solutions
Patient Stories
A baby asleep on a man's shoulder

A seat at the table: One family’s story of finding advanced care for hydrocephalus

To her parents, everything about 6-month-old Stella is a miracle. Rose and Vlad were ecstatic to learn they were expecting a baby after Rose was diagnosed with uterine fibroids. When Stella arrived months early, they were astounded by her ability to keep growing stronger. And when her doctors discovered a buildup of cerebral spinal fluid ... Read More about A seat at the table: One family’s story of finding advanced care for hydrocephalus