Archive for research
Climate and children’s health: A conversation with Dr. Aaron Bernstein
When Boston Children’s Hospital pediatrician Dr. Aaron Bernstein was in medical school, he was told that climate change — an interest of his since 7th grade — belonged in the realm of politics, not medicine. One professor told him flat out, “You’re trying to fit a square peg in a round hole.” But another professor ... Read More about Climate and children’s health: A conversation with Dr. Aaron Bernstein
At the intersection of research and clinical care: Celebrating our female gastroenterologists
In honor of Women’s History Month and National Doctor’s Day, we’re celebrating just a few of the amazing female gastroenterologists at Boston Children’s Hospital. Elizabeth Hait, MD, MPH Elizabeth Hait, MD, MPH Clinical director, Division of Gastroenterology, Hepatology, and Nutrition Co-Medical director, Eosinophilic Gastrointestinal Disease Program Why did you want to become a physician? In ... Read More about At the intersection of research and clinical care: Celebrating our female gastroenterologists
Building a bladder-specific Botox
Botulinum toxins are bacterial neurotoxins that also have a range of therapeutic uses. In urology, injections of these potent substances can relax the bladder muscle, helping treat conditions such as overactive bladder and neurogenic bladder. Of the seven types of botulinum toxin, two have been approved by the U.S. Food and Drug Administration (FDA): botulinum ... Read More about Building a bladder-specific Botox
Open-label placebo offers new treatment for disorders of gut-brain interaction in children
Pain-predominant disorders of gut-brain interaction (DGBIs) in children — such as functional abdominal pain (FAP) and irritable bowel syndrome (IBS) — can lead to disabling symptoms, poor quality of life, and high use of health care resources. While optimal treatment for these conditions remains elusive, we know that this patient population tends to have high ... Read More about Open-label placebo offers new treatment for disorders of gut-brain interaction in children
Can intensive early behavioral therapy help children with Down syndrome?
“It’s like learning a new language. It’s a challenge, but a good challenge,” says Kristala of the new ways she has learned to connect with her 3-year-old son, Ellison, who has Down syndrome. Her favorite part of the Joint-Attention-Symbolic-Play-Engagement-Regulation (JASPER) clinical trial program at Boston Children’s Hospital came during the “Follow His Lead” week. “I ... Read More about Can intensive early behavioral therapy help children with Down syndrome?
Bringing genomics to community NICUs
About a year and a half ago, Robert Rothstein, MD, FAAP encountered a baby with a pattern of facial features and clinical findings that suggested a genetic syndrome. The available tests couldn’t pinpoint a diagnosis, and the family wanted a more definitive answer. So Rothstein and his colleagues transferred the newborn from Baystate Medical Center ... Read More about Bringing genomics to community NICUs
Surviving stem cell transplant: New hope when the donor isn’t a full match
To see Tara Daniels today, with a corporate job in marketing and about to close on a house, you’d never know what she’s been through, how thrilled she is to be alive. This month marks five years since she received a high-risk bone marrow transplant for a life-threatening blood cancer. Tara woke up feeling sick ... Read More about Surviving stem cell transplant: New hope when the donor isn’t a full match
Addressing inequities in asthma by focusing on children’s environments
Asthma strikes children in low-income urban areas especially hard, more often sending them to the hospital. For more than 20 years, Dr. Wanda Phipatanakul at Boston Children’s Hospital has been investigating why — and seeking ways to level the playing field. “Children in low-income areas and children of color often aren’t diagnosed early enough with ... Read More about Addressing inequities in asthma by focusing on children’s environments
It takes a village: Creating best practices for personalized treatments
In 2019, doctors and scientists at Boston Children’s Hospital announced a medical landmark. In the space of one year, a team led by Timothy Yu, MD, PhD, pinpointed a one-of-a-kind genetic mutation in a girl named Mila with Batten disease, developed a custom drug called milasen to repair the mutation, and treated Mila with it. ... Read More about It takes a village: Creating best practices for personalized treatments
Solving neurodevelopmental mysteries, one gene, one child at a time
Suheil Day was born early, at 37 weeks. Aside from a slight head lag and mild muscle weakness, nothing seemed terribly amiss. But as the months progressed, he began having seizures. “At the age of 4 to 5 months, he started waking up screaming and crying excessively, his eyes rolling up into his head,” says ... Read More about Solving neurodevelopmental mysteries, one gene, one child at a time