Health and Parenting
illustration of a porcupine conveys the concept of needle pain

Sticking it to needle pain

Ask any kid what they dread most about a visit to the doctor and you’ll likely hear the same answer: “Needles!” Whether in the form of vaccinations or blood draws, the pain associated with needlesticks isn’t “just a small poke” to many children. It’s a major source of fear and distress — and not just ... Read More about Sticking it to needle pain
Patient Stories
boy with esophageal damage sits on grass

Ready for the next step: Innovative care for Chase

Chase Essex loves pizza and has even prepared shrimp scampi for his family. So it might come as a surprise that, until recently, the 14-year-old hadn’t eaten by mouth for much of his life. “Now,” says his mother, Antoinette, “he eats everything in sight.” More than a decade ago, Chase was like any other curious ... Read More about Ready for the next step: Innovative care for Chase
Clinical Care
chase sits in a garden after a jejunal interposition

Beyond limits: A staged approach to jejunal interposition

By the time Chase Essex arrived at Boston Children’s Hospital in 2016, he had reached what most clinicians would consider the limits of modern medicine. Surgeons at his home hospital had performed nearly three dozen procedures to address damage to his trachea caused by his accidental ingestion of lye years earlier. Yet when it came ... Read More about Beyond limits: A staged approach to jejunal interposition
Health and Parenting
developmental milestones checklists don't always agree.

Developmental milestone checklists don’t always agree, finds study

Developmental milestones, such as sitting unsupported or babbling, are a cornerstone for tracking a child’s development and spotting potential delays. Yet fewer than half of pediatricians actually use formal developmental assessments. Hoping to make the process easier, Carol Wilkinson, MD, PhD, in the Boston Children’s Hospital Division of Developmental Medicine, set out to incorporate a ... Read More about Developmental milestone checklists don’t always agree, finds study
Patient Stories
Morgan, who has hemophilia, poses

Breaking gender biases: What is it like to be a girl with severe hemophilia?

In human biology class this past semester, Morgan DiPrima viewed a PowerPoint presentation that made her head spin. It included a hemophilia slide solely focused on men. “So, I asked the professor if I could do a class presentation on hemophilia for extra credit.” Very few college students “request” extra work, but this 19-year-old Dean ... Read More about Breaking gender biases: What is it like to be a girl with severe hemophilia?
Research
Eric Greer researches epigenetics and epigenetic inheritance

Presidential awardee explores epigenetics via slime molds, worms, and more

Pretty much all of your cells have the same DNA code. Yet they come in an astonishing number of forms. Some cells contract so that your heart can beat or your muscles flex. Others have jobs in your immune system, tuned to recognize different threats. And cells can change their behavior, altering their metabolism for ... Read More about Presidential awardee explores epigenetics via slime molds, worms, and more
Research
shape shifting glioblastoma

Single-cell sequencing reveals glioblastoma’s shape-shifting nature

Glioblastoma, a cancer that arises in the brain’s supporting glial cells, is one of the worst diagnoses a child can receive. The grade IV, highly malignant tumor aggressively infiltrates healthy brain tissue, and most children die of the disease within one to two years of diagnosis, similar to adults. “The current approach is surgical removal, ... Read More about Single-cell sequencing reveals glioblastoma’s shape-shifting nature
Patient Stories
mom holds her aspirating baby

Mia’s team: Working together to address aspiration

Seven-month-old Mia Petrelli sits in a chair in the darkened room. As Kara Larson, a speech language pathologist in the Aerodigestive Center at Boston Children’s Hospital, spoons different foods mixed with liquid barium into the little girl’s mouth, a nearby video screen displays real-time images of her anatomy. It’s part of a modified barium swallow ... Read More about Mia’s team: Working together to address aspiration