Cracking the code on Kleefstra syndrome: It takes a community
Paul Terry is a staunch advocate for people with rare diseases — but researchers were only able to put a name to his condition five years ago. It was an answer he and his family had long sought. When Paul was a baby, his parents saw that he wasn’t hitting all his milestones. Their pediatrician ... Read More about Cracking the code on Kleefstra syndrome: It takes a community
Reconstructing a chest wall, one virtual step at a time
It takes a village of clinicians and engineers to reconstruct a chest wall. It also takes a lot of 3D modeling. A young girl needed to have her chest wall restructured to stop life-threatening airway obstruction. To ensure the complicated operation would be efficient, Emily Eickhoff, a Boston Children’s biomedical engineer, partnered with a team ... Read More about Reconstructing a chest wall, one virtual step at a time
Researchers look for ways to start puberty ‘on time’
Children who experience early puberty or delayed puberty may be at risk of having shortened height as adults. They may also feel emotionally unprepared for the changes of puberty, and may feel self-conscious or experience social anxieties as a result. To address this challenge, Boston Children’s researchers are trying to further the study of an important genetic player in ... Read More about Researchers look for ways to start puberty ‘on time’
Healthy behaviors may counteract the long-term effects of concussions
When it comes to football, concussion, and long-term health, many people have already made up their minds: They believe that repeat concussions condemn athletes to a future of mental illness and cognitive decline. Such beliefs instill fear and helplessness in many professional athletes and their families. “There’s a thought that former NFL players are all ... Read More about Healthy behaviors may counteract the long-term effects of concussions
Babies and screen time: New research calls for caution
If you’re a parent, you’ve probably been there. You have a baby howling for attention, but you need to cook dinner or get a sibling to take a much-needed nap. Baby TV shows, touch tablets, and digital phone toys can feel like lifesavers in keeping an active infant calm and contained while juggling what life ... Read More about Babies and screen time: New research calls for caution
New research discovery could shorten ICU stays for children with diabetic ketoacidosis
When a child with diabetic ketoacidosis (DKA) requires intensive care, clinicians often monitor blood ketone levels to determine whether treatment has successfully reversed the abnormal ketone production. Yet, the utility of blood ketone levels to diagnose DKA or determine whether a child’s DKA has resolved have not been rigorously studied. But now, research by Elise Tremblay, ... Read More about New research discovery could shorten ICU stays for children with diabetic ketoacidosis
Teens aren’t small adults: Rethinking surgical treatment of adolescent clavicle fracture
Until about 15 years ago, most clavicle fractures were allowed to heal with minimal medical intervention. That changed after a 2007 study reported better shoulder function after plate-fixation surgery. Although the study participants were adults, the rate of surgical treatment subsequently increased across all age groups. Now, a landmark study at Boston Children’s Hospital demonstrates ... Read More about Teens aren’t small adults: Rethinking surgical treatment of adolescent clavicle fracture
Does thyroid cancer in children behave differently than in adults?
Once relatively uncommon, pediatric thyroid cancer is increasing among children and is now the most common type of cancer diagnosed in adolescents. As the oldest program of its kind in the U.S. — and one of the only centers dedicated to pediatric thyroid disease — Boston Children’s Thyroid Center is at the forefront of research on ... Read More about Does thyroid cancer in children behave differently than in adults?
A heart valve that grows along with a child could reduce invasive surgeries
Clinical trials have started for the first prosthetic pulmonary valve replacement that is specifically designed for pediatric patients and can expand over time inside a child’s anatomy. Instead of having invasive replacement surgeries every few years, as is the practice now, a child can have the valve fitted to their individual body size and, if ... Read More about A heart valve that grows along with a child could reduce invasive surgeries
Research 2022: Tackling disease in new ways
Researchers across Boston Children’s spent 2022 imagining new solutions to old challenges in health and medicine, opening the door to brand-new treatments. Here are a few areas where research is poised to make a difference in children’s — and even adults’ — lives. Rethinking disease through genetics Genetic sequencing is becoming a fundamental tool for discovering ... Read More about Research 2022: Tackling disease in new ways