☰
  • Request an Appointment
  • Get a Second Opinion
  • Share Your Story
  • Donate
Close
  • Home
  • Research
  • Patient Stories
  • Parenting
  • Clinical Care
  • Our Community
  • Request an Appointment
  • Get a Second Opinion
  • Share Your Story
  • Donate

Answers
Your destination for kids' health

A woman doubled over in pain, holding her abdomen.

A better treatment for endometriosis could lie in migraine medications

Basic/Translational
Endometriosis is a common, mysterious, often painful condition in which tissue similar to the uterine lining grows outside the uterus, forming lesions in locations such as the fallopian tubes, ovaries, and pelvis. These lesions can cause severe pain during periods, heavy menstrual bleeding, pelvic or abdominal pain, and sometimes painful bowel movements and urination. Existing ... Read More about A better treatment for endometriosis could lie in migraine medications
Tagged: adolescent medicine, endometriosis, gynecology, neuroinflammation, vascular biology
Izadifar in the lab, working with an organ chip under a hood

Modeling urinary tract disorders on a chip: Zohreh Izadifar

Basic/Translational, Research
When a new tissue sample arrives from the Department of Urology, the Boston Children’s Hospital lab of Zohreh Izadifar, PhD springs into action. The tissue, from a child with urinary tract pathology, is whisked into the tissue culture room. Under a hood, lab members Dasvit Shetty, PhD, and Gretchen Carpenter, MSc, carefully isolate the cells ... Read More about Modeling urinary tract disorders on a chip: Zohreh Izadifar
Tagged: bioengineering, biomaterials and drug delivery, organoids, research rising stars, tissue engineering, urinary tract infection, urology
A virus superimposed on the intestine, with chain links.

A surprising link between Crohn’s disease and the Epstein-Barr virus

Clinical, Research
Crohn’s disease, a debilitating inflammatory bowel disease, has many known contributing factors, including bacterial changes in the microbiome that foster an inflammatory environment. Now, for the first time, Crohn’s disease been tied to a virus — specifically, Epstein-Barr virus (EBV), best known for causing infectious mononucleosis (mono). Researchers had already observed increased levels of EBV ... Read More about A surprising link between Crohn’s disease and the Epstein-Barr virus
Tagged: crohn's disease, immunology, infectious diseases, inflammatory bowel disease
A child with type 1 diabetes testing her blood glucose via finger prick.

Addressing food insecurity and nutrition challenges in pediatric type 1 diabetes care

Research
Managing type 1 diabetes can be overwhelming for children and families. As children learn to live with the disease, many cut back on visits to their nutritionists. Others face barriers like food insecurity that make it difficult to maintain a balanced diet. And without the proper professional support and access to healthy foods, children’s overall ... Read More about Addressing food insecurity and nutrition challenges in pediatric type 1 diabetes care
Tagged: diabetes, endocrinology, nutrition, research
Drawing of a nerve ending with macrophages clustered at the axon tips.

Could peripheral neuropathy be stopped before it starts?

Basic/Translational, Research
An increase in high-fat, high-fructose foods in people’s diets has contributed to a dramatic increase in type 2 diabetes. This, in turn, has led to an increase in peripheral neuropathy — nerve damage, typically in the hands and feet — that causes weakness, loss of sensation and, in some, a stabbing, burning, or tingling pain. ... Read More about Could peripheral neuropathy be stopped before it starts?
Tagged: diabetes, immunology, neurology, neuroscience
Arrows show the flow of blood on an illustration of the heart.

It’s all in the PV loops: New analytical model could improve circulation assessments before heart surgery

Clinical, Research
The double-switch operation corrects the congenital reversal of the heart’s ventricles and its two main arteries. It’s a practical way of putting the ventricles into the position they belong so that children with congenitally corrected transposition of the great arteries (CC-TGA) can benefit from enhanced circulation. Surgery, though, doesn’t come without risks. Some children’s left ventricles — ... Read More about It’s all in the PV loops: New analytical model could improve circulation assessments before heart surgery
Tagged: blood, cardiac research, cardiac surgery, cardiology, complex biventricular repair, congenital heart defect, heart, heart center, research
Lungs with macrophages in the airways, illustrating the concept of macrophage-based therapy for pulmonary hypertension.

Modifying macrophages in the lung could head off pulmonary hypertension

Basic/Translational, Research
In the 1980s, when Stella Kourembanas, MD, began her career in neonatology, she cared for newborns with pulmonary hypertension, a disease that results in abnormally high blood pressure in the lung arteries and can lead to heart failure. Since then, treatments like inhaled nitric oxide, new vasodilators, new modalities of mechanical ventilation, and extracorporeal membrane ... Read More about Modifying macrophages in the lung could head off pulmonary hypertension
Tagged: bronchopulmonary dysplasia, lung disease, newborn medicine, pulmonary hypertension
Hundreds of dots representing RNAs, forming the shape of an E. coli bacterium.

A new tool could exponentially expand our understanding of bacteria

Basic/Translational, Research
How do bacteria — harmless ones living in our bodies, or those that cause disease — organize their activities? A new study, combining powerful genomic-scale microscopy with a technical innovation, captured which genes bacteria turn on in different situations and in different spatial environments. The technology, described January 23 in Science, promises to take the ... Read More about A new tool could exponentially expand our understanding of bacteria
Tagged: antibiotics, genetics and genomics, imaging, microbes, microbiome
A parent holds a newborn infant.

MRI could reduce the mystery of brachial plexus injuries in infants

Clinical, Research
About one in 1,000 children are born with brachial plexus birth injury (BPBI), upper extremity weakness or paralysis resulting from trauma to the brachial plexus nerves during childbirth. Most children with BPBI recover with observation and minimally invasive care, but about 30 percent have injuries severe enough to lead to long-term impairment. Thanks to recent ... Read More about MRI could reduce the mystery of brachial plexus injuries in infants
Tagged: brachial plexus, hand and upper extremity, neurosurgery, orthopedics, research
Alston holds up a tray of tubes.

Bringing order to disorder: Jhullian Alston, PhD

People, Research
Proteins typically fold into orderly, predictable three-dimensional structures that dictate how they will interact with other molecules. Jhulian Alston, PhD, is drawn to intrinsically disordered proteins, whose key feature is a lack of structure. They are difficult to study and far less explored. “They’re floppy, they don’t have specific folds, they can’t slot into each ... Read More about Bringing order to disorder: Jhullian Alston, PhD
Tagged: cellular and molecular medicine, proteomics, research rising stars

Posts navigation

Older posts
Newer posts

Stay connected!

Sign up for our weekly email newsletter for the latest parenting tips, patient stories, and news for your family from Boston Children's

 

Subscribe now
Clinical Trials
Connect With Boston Children’s Hospital
U.S. News U.S. News
    • 300 Longwood Avenue, Boston, MA 02115

    • 617-355-6000 800-355-7944

  • How Can We Help

    • International Visitors
    • Centers and Services
    • Conditions + Treatments
    • Find a Doctor
    • Get a Second Opinion
    • Locations
  • About

    • About Us
    • Giving to Boston Children’s
    • Newsroom
    • Quality & Patient Safety
  • Legal

    • HIPAA Notice of Privacy Practices
    • Patient & Family Rights
    • Terms of Use
    • Public Policy