Archive for endocrinology
Study shows young adults don’t easily transition to self-care of diabetes
Diabetes is challenging to manage at any age, but even more so for young adults who are handling the condition on their own for the first time. They need to transition from pediatric to adult care as smoothly as possible — but a recent study finds this isn’t happening. Research led by Katharine Garvey, MD, MPH, ... Read More
Tagged: diabetes, emergency medicine, endocrinology, research
Going out of the box to tackle pancreatic cancer
Pancreatic cancers are deadly and hard to treat, in part because they are so often detected at an advanced stage; overall five-year survival rates are about 11 percent. Two separate labs at Boston Children’s Hospital took out-of-the-box approaches to this difficult cancer, and both uncovered some very promising leads. Wiping out pancreatic tumors’ immune defense ... Read More
Congenital hypothyroidism: New guidance for clinicians
Congenital hypothyroidism is usually caused by a baby being born with an absent or underactive thyroid gland. When not treated, it’s one of the most common preventable causes of intellectual disability. Although newborn screening can identify congenital hypothyroidism and lead to prompt treatment, an estimated 70 percent of newborns worldwide are born in regions that ... Read More
Tagged: endocrinology, research
Researchers look for ways to start puberty ‘on time’
Children who experience early puberty or delayed puberty may be at risk of having shortened height as adults. They may also feel emotionally unprepared for the changes of puberty, and may feel self-conscious or experience social anxieties as a result. To address this challenge, Boston Children’s researchers are trying to further the study of an important genetic player in ... Read More
Tagged: adolescent medicine, endocrinology, primary care
Explaining endometriosis: What parents and teens should know
People with uteruses know that menstruation can bring cramps, general discomfort, mood swings, and other symptoms each month. But, just how much discomfort and pain is normal during your period? For more insights on severe period pain — and endometriosis in particular — we spoke with Dr. Jessica Shim in the Division of Gynecology and ... Read More
Tagged: adolescent medicine, endocrinology
The genetics of height: Coming close to cracking the code
More than 20 years ago, as a pediatric endocrinology fellow at Boston Children’s, Joel Hirschhorn, MD, PhD, saw many children with unusually short stature, and would often tell parents that their child was growing slowly because of genetic factors. But no height-related genes had yet been identified — in fact, scientists believed there were so ... Read More
Out of balance: How hormones can affect your child’s period
If your tween or teen is experiencing irregular periods, they aren’t alone. In the first two years after getting a period, you should expect fluctuation in cycle length and the number of days their period lasts. However, there are period symptoms that go beyond what makes a “normal” irregular period. If your child’s period hasn’t ... Read More
Tagged: adolescent medicine, endocrinology, primary care
Genetic risk factors for PCOS act independently of ovarian function
It’s estimated that as many as 10 percent of women have polycystic ovary syndrome (PCOS), a hormonal condition that produces symptoms such as infertility, irregular menstrual periods, and excessive body hair growth. Women with PCOS are also at increased risk for cardiometabolic dysfunction, as evidenced by insulin resistance and obesity. Yet, despite extensive studies of PCOS, ... Read More
Tagged: diabetes, endocrinology, metabolism, obesity
Can we harness intestinal cells to treat endocrine disorders?
Enteroendocrine cells punch above their weight. Comprising just about 1 percent of intestinal cells, they produce, as a group, around 15 different hormones. These not only regulate intestinal function and digestion, but also influence metabolic functions like insulin secretion and appetite regulation. A new technology platform developed at Boston Children’s could set the stage for ... Read More
Tagged: diabetes, endocrinology, obesity, organoids, stem cells
A coming wave of diabetes? The link with COVID-19
Researchers are observing a new long-term health concern in patients hospitalized with COVID-19 — an increase in new-onset hyperglycemia lasting months after infection. An Italian study found that about half of the patients admitted to the hospital for COVID-19 during the start of the pandemic had new cases of hyperglycemia, or high levels of blood ... Read More
Tagged: coronavirus, diabetes, endocrinology, pancreatic disorders, research