Archive for Alice McCarthy
New strategies for restoring myelin on damaged nerve cells
Key takeaways Myelin is an essential fatty substance coating surrounding nerve axons. After injury, regenerated nerve axons usually fail to remyelinate, inhibiting nerve cell communication. A combination treatment led to remyelination in about 60 percent of regenerated axons. This research may have implications in other diseases associated with myelin loss, like multiple sclerosis. Loss of ... Read More about New strategies for restoring myelin on damaged nerve cells
Tagged: multiple sclerosis, nerve injury, neurology, neuroscience, research
COVID-19 virus levels in children: Differences between asymptomatic vs. symptomatic kids
A new study finds that most asymptomatic children who tested positive for COVID-19 had lower levels of the virus compared to symptomatic children. While it is the first large and comprehensive investigation of its kind in asymptomatic children, several important questions remain unanswered. Nira Pollock “Our study did show that asymptomatic children had lower viral ... Read More about COVID-19 virus levels in children: Differences between asymptomatic vs. symptomatic kids
Tagged: coronavirus, research
A COVID-19 DNA nanoswitch: A new kind of test for a new kind of virus
When the COVID-19 pandemic shut down research laboratories across the country, several labs at Boston Children’s Hospital geared up, including that of Wesley Wong, PhD. He and his team responded to the threat by developing a new, easy diagnostic test for COVID-19. Wesley Wong “Our technology, a DNA nanoswitch, is a new way of probing ... Read More about A COVID-19 DNA nanoswitch: A new kind of test for a new kind of virus
Tagged: coronavirus, diagnostics
Language barriers linked with medical errors in hospitalized children
A new study finds that hospitalized children whose families have limited comfort with English are twice as likely to experience medical errors. The study, which did not include patient data from Boston Children’s Hospital, highlights the need for improving communication between these families and the health care providers they interact with to ensure the safety ... Read More about Language barriers linked with medical errors in hospitalized children
Tagged: culture, health equity, medical training, research
As COVID-19 fuels opioid deaths, researchers look to create an anti-opioid vaccine
A project that began one year ago at Boston Children’s Hospital to develop an anti-opioid vaccine is starting to bear its first fruits. A team of addiction experts and vaccine developers across the Boston Children’s research community were recently awarded a $25 million research contract from the NIH’s Helping to End Addiction Long-term Initiative, or NIH ... Read More about As COVID-19 fuels opioid deaths, researchers look to create an anti-opioid vaccine
Tagged: adolescent medicine, opioids, substance abuse, vaccines
Scar-free healing after spinal cord injury relies on specialized cells
Key takeaways Scar tissue prevents nerves from communicating with each other. Microglia cells in the central nervous system help prevent scar tissue formation after spinal cord injuries in newborn mice. Transplanted newborn microglia cells drastically reduced scar formation in adult mice with spinal cord injury, opening the door to new treatment possibilities. One of the ... Read More about Scar-free healing after spinal cord injury relies on specialized cells
Tagged: nerve injury, neurology, neuroscience, spinal cord injury
Pain neurons activate immune cells, opening new treatment possibilities
For a long time, pain and inflammation were thought to be two separate biological responses. But new research by Boston Children’s Hospital and international collaborators suggests that the same sensory neurons that produce pain also trigger inflammation. And they do so by activating cells of the immune system, a relationship never described before. This interaction ... Read More about Pain neurons activate immune cells, opening new treatment possibilities
Tagged: immunology, neuroinflammation, pain
Global partnership leads to improved treatment for childhood diarrhea
Diarrheal diseases remain a major childhood health problem in many parts of the world. Each year, they lead to the deaths of more than 500,000 children under age 5 globally. A new large clinical trial based in Tanzania and India, led by investigators at Boston Children’s Hospital, local research universities, and the World Health Organization ... Read More about Global partnership leads to improved treatment for childhood diarrhea
Tagged: clinical trials, gastroenterology, global health
Social distancing: Benefits beyond COVID-19
During COVID-19, social distancing has largely kept children away from school, daycare, and other contact with friends. But even though social distancing may be difficult and annoying, new research from Boston Children’s Hospital shows it has proven benefits beyond preventing COVID-19; it also helps stop the spread of other common childhood infections, like flu. “Any ... Read More about Social distancing: Benefits beyond COVID-19
Tagged: coronavirus, infectious diseases, research
COVID-19 tests: What families should know
As schools and businesses are looking to safely reopen during the COVID-19 pandemic, we’re hearing more about testing for COVID-19. But there isn’t just one “COVID-19 test.” All of the tests have one goal: to detect whether someone is or has been infected with the SARS-CoV-2 virus that causes COVID-19. But they work in different ... Read More about COVID-19 tests: What families should know
Tagged: coronavirus, diagnostics, research