Archive for Alice McCarthy
Therapy developed at Boston Children’s stops preeclampsia before it starts
Preeclampsia occurs in about 3 to 5 percent of all pregnancies. Characterized by very high maternal blood pressure, it can lead to serious, sometimes fatal, complications in both mother and baby. In severe cases, early delivery is often the only effective treatment, usually before the baby’s lungs are fully developed. Researchers within the Division of ... Read More about Therapy developed at Boston Children’s stops preeclampsia before it starts
The new COVID-19 virus variant: What you need to know
You’ve probably seen news reports about B.1.1.7, a newly discovered version of the SARS-CoV-2 virus that causes COVID-19. Now found in several countries, including the U.S., B.1.1.7 is quickly spreading around the world. Although B.1.1.7 seems to be more contagious, it doesn’t appear to lead to more serious illness. What else do we know about ... Read More about The new COVID-19 virus variant: What you need to know
COVID-19 vaccines: Do you know myth from fact?
Two COVID-19 vaccines — from Pfizer/BioNTtech and Moderna — have received emergency use authorization in the United States by the U.S. Food and Drug Administration (FDA). Many more are in various stages of development around the world. Several of these are in the final stage of clinical trials and could be submitted for formal authorization ... Read More about COVID-19 vaccines: Do you know myth from fact?
Low-carb diets for diabetes: Rediscovering centuries-old wisdom
This year represents the 100th anniversary of the discovery of insulin, a hormone that regulates the amount of glucose, or sugar, in the blood. While insulin medications have literally been life-savers for many kids and adults with diabetes, diets that help keep blood sugar levels steady are often overlooked for controlling diabetes. These diets, often ... Read More about Low-carb diets for diabetes: Rediscovering centuries-old wisdom
It’s personal: How the Boston Children’s progeria research community brought new life to an old drug
In late November, the U.S. Food and Drug Administration (FDA) approved a repurposed cancer drug called lonafarnib to treat Hutchinson-Gilford progeria syndrome, better known as progeria — an ultra-rare incurable genetic disease associated with rapid aging. On average, children with progeria die before age 15, usually the result of rapidly accelerated atherosclerosis resulting in heart ... Read More about It’s personal: How the Boston Children’s progeria research community brought new life to an old drug
In-hospital telehealth: Care innovation during the COVID-19 pandemic
The quick response, or QR, code — that square barcode symbol used by smartphone apps to link users with specific information — became an unexpected but essential tool for patient care at Boston Children’s Hospital in early spring. When the first patients with COVID-19 arrived, it quickly became clear that health care providers needed safer ... Read More about In-hospital telehealth: Care innovation during the COVID-19 pandemic
Avoiding a dangerous attraction to magnets: Lainey’s story
A few days before Valentine’s Day in 2013, 2-year-old Lainey Styles wasn’t feeling well. She had vomited, was lethargic, and had a fever. After visiting the pediatrician, her mother Jessica thought Lainey had a stomach virus. But the appearance of a softball size bruise around Lainey’s belly button a couple of days later prompted her ... Read More about Avoiding a dangerous attraction to magnets: Lainey’s story
The new COVID-19 vaccines: Will they be safe?
Just within the past week, pharmaceutical companies have announced encouraging news about two COVID-19 vaccines in the final development phase. As more vaccine developers announce similar reports in the coming weeks and months, it’s key to remember that vaccine safety is as important as effectiveness against the virus. Fortunately, scientists have learned lessons from the ... Read More about The new COVID-19 vaccines: Will they be safe?
Tau protein changes correlate with Alzheimer’s disease dementia stage
Research into Alzheimer’s disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients’ brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain. Key takeaways A pathological form of the tau protein contributes to the ... Read More about Tau protein changes correlate with Alzheimer’s disease dementia stage
Chromatin regulation enables generation of diverse antibodies
We need a variety of antibody types to help fight off invading foreign pathogens and our genome is exquisitely tuned to produce them to meet emerging needs. A new study finds that not just our DNA, but its configuration and packaging, help us generate diverse antibodies. Key takeaways Chromatin loop extrusion leads to creation of ... Read More about Chromatin regulation enables generation of diverse antibodies