Clinical Care
Cartoon illustration showing the different steps for developing personalized drugs: genetic testing, laboratory work, drug formulation, and treating a patient.

It takes a village: Creating best practices for personalized treatments

In 2019, doctors and scientists at Boston Children’s Hospital announced a medical landmark. In the space of one year, a team led by Timothy Yu, MD, PhD, pinpointed a one-of-a-kind genetic mutation in a girl named Mila with Batten disease, developed a custom drug called milasen to repair the mutation, and treated Mila with it. ... Read More about It takes a village: Creating best practices for personalized treatments
Research
Storm (now deceased) and his sister Freja

Solving neurodevelopmental mysteries, one gene, one child at a time

Suheil Day was born early, at 37 weeks. Aside from a slight head lag and mild muscle weakness, nothing seemed terribly amiss. But as the months progressed, he began having seizures. “At the age of 4 to 5 months, he started waking up screaming and crying excessively, his eyes rolling up into his head,” says ... Read More about Solving neurodevelopmental mysteries, one gene, one child at a time
Patient Stories
two side-by-side images of drew ice skating at an indoor rink

Care for post-COVID symptoms helps get figure skater back in the rink

Drew Kenney is no stranger to the ice. As a local and national competitive figure skater, the 16-year-old executes double salchows, double flips, and axels with ease. So when she began to feel winded — and then started falling — at the rink last fall, she knew something was wrong. “At first we thought she ... Read More about Care for post-COVID symptoms helps get figure skater back in the rink
Health and Parenting
kyle and tyler pose with wally the green monster mascot. they are all wearing red sox shirts

‘Feeling empowered’: How vaccination helped me care for my family when one son got COVID-19

In mid-November, I awoke to an email from my children’s school stating that my second grader, Kyle, had been a close contact of someone who tested positive for COVID-19. I wasn’t overly concerned. While this was the first “close contact” email we had received, we had previously been notified that both our children were in ... Read More about ‘Feeling empowered’: How vaccination helped me care for my family when one son got COVID-19
Health and Parenting
People at a dining table fill their plates with food.

Pass the pie and a mask: COVID-19 safety tips for the holidays

This holiday season will seem different than the last one — but it’s still not the season to blissfully ignore health and safety measures that combat COVID-19. Thanks to the availability of COVID-19 vaccines, families shouldn’t feel obligated to repeat last year’s unprecedented public health guidance to hunker down at home for the holidays. This ... Read More about Pass the pie and a mask: COVID-19 safety tips for the holidays
Health and Parenting
Two adults and a child with presents and a holiday

Returning to holiday chaos: Preventing anxiety in kids

After taking last year “off,” many families are preparing to dive back into holiday busyness, and with it, holiday stress. But what has the time away from crowds, travel, and extended family done to kids’ abilities to enjoy the yuletide cheer? Here, psychologist Dr. Lauren DiLullo with the Department of Psychiatry and Behavioral Sciences, answers ... Read More about Returning to holiday chaos: Preventing anxiety in kids
Research
Illustration of a child having trouble sleeping, with a doodle suggesting disorganization of their brain

Sound sleep, sound mind: The importance of sleep for preteens’ developing brains

When your preteen doesn’t get enough sound sleep, some of the signs, like crankiness, are obvious. But some of the effects are more subtle. A large, first-of-its-kind study from Boston Children’s Hospital now shows that too little or poor-quality sleep may prevent the brain from developing strong, efficient connections. “Early adolescence is a critical time ... Read More about Sound sleep, sound mind: The importance of sleep for preteens’ developing brains
Health and Parenting
A swaddled baby in a crib

Sweet dreams: A guide to infant sleep

While sleep should be peaceful, ensuring your baby is sleeping safely — and soundly — can be stressful. We spoke with Shana Zandman, MD, a pediatrician at Brookline Pediatrics in the Boston Children’s Primary Care Alliance, and Jennifer Gingrasfield, RN, MSN, a pediatric nurse practitioner in the Sleep Center at Boston Children’s Hospital, about creating ... Read More about Sweet dreams: A guide to infant sleep
Health and Parenting
Altered seflie-image.

Help kids fight the “Selfie Effect” and build self-esteem instead

It may be hard to imagine now, but there was a time not too long ago when social media didn’t exist and we didn’t have cameras on our phones. But today, some of the most widely used social media platforms influence not only how we communicate with the world, but how we think the world ... Read More about Help kids fight the “Selfie Effect” and build self-esteem instead