Search Results for: cancer
The softer the nanoparticle, the better the drug delivery to tumors
For the first time, scientists have shown that the elasticity of nanoparticles can affect how cells take them up in …Read More
Sickle cell gene therapy to boost fetal hemoglobin: A 70-year timeline of discovery
Boston Children’s Hospital is now enrolling patients age 3 to 35 in a clinical trial of gene therapy for sickle cell …Read More
Taking a sideswipe at high-risk neuroblastoma
Cancer and other diseases are now understood to spring from a complex interplay of biological factors rather than any one …Read More
Gene therapy halts progression of cerebral adrenoleukodystrophy in clinical trial
Adrenoleukodystrophy — depicted in the 1992 movie “Lorenzo’s Oil” — is a genetic disease that most severely affects boys. Caused by …Read More
To monitor health, simply trip the ‘nanoswitches’
“Nanoswitches” — engineered, shape-changing strands of DNA — could shake up the way we monitor our health, according to new …Read More
Landmark moment for science as the FDA approves a gene therapy for the first time
Today, the Food and Drug Administration approved a gene therapy known as CAR T-cell therapy that genetically modifies a patient’s own cells …Read More
Medical milestone: Making blood stem cells in the lab
Pluripotent stem cells can make virtually every cell type in the body. But until now, one type has remained elusive: …Read More
Entry door for deadly C. difficile toxin suggests new mode of protection
Clostridium difficile, also called “C. diff,” tops the CDC’s list of urgent drug-resistant threats. Marked by severe diarrhea and intestinal inflammation, C. …Read More
Keeping up with HIV mutations: Building a nimble vaccine test system
An AIDS vaccine able to fight any HIV strain has thus far eluded science. HIV frequently mutates its coat protein, …Read More
BCL11A-based gene therapy for sickle cell disease passes key preclinical test
Research going back to the 1980s has shown that sickle cell disease is milder in people whose red blood cells carry a …Read More