Search Results for: "program in cellular and molecular medicine"
Protecting against HIV by tricking the immune system
In making an HIV vaccine, a major goal is to stimulate production of broadly neutralizing antibodies that can fight multiple …Read More
Boosting host immune defenses to treat tuberculosis
Current treatment regimens for Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, are long, complex, and hard for people to …Read More
Unlocking antibody diversity: chromatin loops, V(D)J recombination, and class switching
A new study from the laboratory of Frederick Alt, PhD, of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children’s …Read More
Targeting a rogue T cell prevents and reverses multiple sclerosis in mice
Multiple sclerosis is an autoimmune disease affecting both adults and children. It’s driven by “helper” T cells, white blood cells …Read More
How new loops in DNA packaging help us make diverse antibodies
Diversity is good, especially when it comes to antibodies. It’s long been known that a gene assembly process called V(D)J …Read More
PET imaging shows if PD-1 cancer immunotherapy is working
PD-1 is a protein on our T cells that normally keeps these immune cells from running amok. A growing number …Read More
Existing anti-parasitic drug could offer a treatment for Ebola
Amid the worsening Ebola outbreak in the Congo, now threatening to spill into Rwanda, a new study suggests that an …Read More
Presidential awardee explores epigenetics via slime molds, worms, and more
Pretty much all of your cells have the same DNA code. Yet they come in an astonishing number of forms. …Read More
First sharp images reveal structure of key inflammatory protein
After decades of attempts by the scientific community, researchers have now provided the first clear look at a protein implicated …Read More
New technique images whole brains with incredible resolution
Decades ago, discoveries about the brain’s intricate anatomy were made with careful dissection and drawings. Today, they’re made with super-resolution …Read More