Archive for lymphoma
Tackling an aggressive, treatment-resistant lymphoma where it lives
Anaplastic large cell lymphoma, a form of non-Hodgkin lymphoma, is the most common aggressive lymphoma in children. Chemotherapy and radiation fail to cure about 30 percent of cases. When tumors are driven by the oncogene ALK — which is the case for the majority of children — kinase inhibitor drugs like crizotinib are very effective ... Read More about Tackling an aggressive, treatment-resistant lymphoma where it lives
Making ready-made CAR T cells for cancer immunotherapy
In CAR T-cell immunotherapy, T cells from a patient’s own blood are engineered to carry so-called chimeric antigen receptors (CAR) that enable the T cells to attack and kill tumor cells. While CAR-T therapy is a powerful approach for certain leukemias and lymphomas, it’s not available for many patients who need it. It can be ... Read More about Making ready-made CAR T cells for cancer immunotherapy
Crista forms lifelong friendship with her cancer doctor
It’s impossible not to notice the connection between Crista Cardillo and Dr. Kim Stegmaier. The way they laugh and swap stories might make you think they grew up down the street from one another. But their friendship began differently than most: as patient and oncologist at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. When Crista was ... Read More about Crista forms lifelong friendship with her cancer doctor