Cancer, particularly metastatic cancer, can be added to the list of medical conditions that pose a significant risk of worse COVID-19 outcomes , suggests a new study. Led by Boston Children’s Hospital and Zhongnan Hospital of Wuhan University, it represents the first large cohort study to examine COVID-19 outcomes in cancer patients. Findings were published ... Read More about Adults with cancer appear more vulnerable to COVID-19
Tumors have figured out various ways to prevent the immune system from attacking them. Medicine, for its part, has fought back with cancer immunotherapy. The major approach uses checkpoint inhibitors, drugs that help the immune system recognize cancer cells as foreign. Another method, CAR T-cell therapy, directly engineers peoples’ T cells to efficiently recognize cancer ... Read More about Gasdermin E: A new approach to cancer immunotherapy
In 1998, when Timothy Hla, PhD, and his colleagues identified and cloned the receptor for sphingosine-1-phosphate (S1P), it generated a lot of excitement. S1P, a lipid originally discovered in the 1960s, was known to play various roles in the body and in disease. But it wasn’t thought that lipids could have receptors, and it wasn’t ... Read More about S1P and its receptor: New approaches to cancer?
PD-1 is a protein on our T cells that normally keeps these immune cells from running amok. A growing number of cancer drugs are designed to inhibit PD-1, enabling patients’ T-cells to attack and kill cancerous cells. PD-1 blockers such as pembrolizumab (Keytruda) have been helpful in treating several cancers including melanoma, non-small cell lung ... Read More about PET imaging shows if PD-1 cancer immunotherapy is working
A study last week in The New England Journal of Medicine suggests that exposing infants to peanuts can provide lasting protection against peanut allergy. But what about peanut-allergic children right now? They and their parents live a life of precautions — from pre-screening birthday party menus to segregation at the school lunch table — to ... Read More about 20-week treatment makes life safer for kids with peanut allergy