Health and Parenting
Two footprints that show various activities that could increase your risk for COVID-19, including dining out, going to a gym, and going to a movie theater

Hunker down and reduce your ‘transmission footprint’

In the midst of one of the worst COVID-19 surges so far, we finally have some good news. Two coronavirus vaccines, made by pharmaceutical companies Pfizer and Moderna, appear to be highly effective and safe. While data are still preliminary, it seems that the Pfizer vaccine may also have excellent efficacy in older adults. While ... Read More about Hunker down and reduce your ‘transmission footprint’
Research
image of a clinician holding up strands of a gel adhesive

Tough yet flexible: Biologically inspired adhesive may improve fetal surgery

In children with spina bifida, the neural tube that forms the spinal cord and brain doesn’t close during early prenatal development. That leaves the nerves of the spinal cord exposed to potential damage from fetal movement and the surrounding amniotic fluid. While surgeons can repair spina bifida soon after birth, the ideal would be to ... Read More about Tough yet flexible: Biologically inspired adhesive may improve fetal surgery
Research
Poverty and child cancer outcomes

Poverty predicts worse cancer outcomes, even in children receiving top-tier care

A pair of recent studies suggests that even among patients receiving advanced cancer care, poverty is a predictor of worse outcomes. The disturbing findings raise many questions that follow-up studies are now exploring. Key takeaways Poverty was associated with 3.7-fold higher mortality among children receiving targeted immunotherapy for high-risk neuroblastoma. Household poverty was associated with ... Read More about Poverty predicts worse cancer outcomes, even in children receiving top-tier care
Research
Illustration of vaccine bottle surrounded with images of diverse people

The new COVID-19 vaccines: Will they be safe?

Just within the past week, pharmaceutical companies have announced encouraging news about two COVID-19 vaccines in the final development phase. As more vaccine developers announce similar reports in the coming weeks and months, it’s key to remember that vaccine safety is as important as effectiveness against the virus. Fortunately, scientists have learned lessons from the ... Read More about The new COVID-19 vaccines: Will they be safe?
Research
missed signals concept

Missed signals? A new way we vary from each other biologically

Genetics has made huge strides over the past 20 years, from the sequencing of the human genome to a growing understanding of factors that turn genes on and off, namely transcription factors and the DNA “enhancer” sequences they bind to. New research from Boston Children’s Hospital introduces another previously unknown layer of human genetics. It ... Read More about Missed signals? A new way we vary from each other biologically
Research
antibiotic resistance vs temperature in Europe

Rising global temperatures tied to rising antibiotic resistance

A new data analysis suggests that two rising public health threats — climate change and antibiotic resistance — are related. The study, spanning 2000 to 2016, doesn’t establish cause and effect. But its findings, in the journal Eurosurveillance, suggest that rising global temperatures could be helping to fuel increases in antibiotic-resistant bacteria. Key takeaway Countries ... Read More about Rising global temperatures tied to rising antibiotic resistance
Research
illustration of tau protein strands with chemical modifications attached in the brain wit

Tau protein changes correlate with Alzheimer’s disease dementia stage

Research into Alzheimer’s disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients’ brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain. Key takeaways A pathological form of the tau protein contributes to the ... Read More about Tau protein changes correlate with Alzheimer’s disease dementia stage
Health and Parenting
photo of the sun rising over a snowy, tree-filled landscape

How will the winter darkness affect kids’ learning and sleep this year?

The recent fall back of the clocks marked the official end of daylight saving time (DST). It also marks the beginning of the season of shorter days and darker evenings. For many of us, this makes it harder to spend time outside. So, what effect will the increasing darkness have on kids and teens as ... Read More about How will the winter darkness affect kids’ learning and sleep this year?
Patient Stories
La familia Cáceres en Boston Children's en 2010

Un renacimiento en Boston: la terapia genética cumple 10 años

Read the English version. El 17 de diciembre se cumple una década desde que Agustín Cáceres “renació”. Así describen sus padres, Alberto y Marcela, el día en que su hijo recibió su nuevo gen. Nacido en 2010 con inmunodeficiencia combinada grave ligada al cromosoma X (SCID-X1), Agustín pasó los primeros meses de su vida en ... Read More about Un renacimiento en Boston: la terapia genética cumple 10 años