Search Results for: cancer
After 80 years, genetic causes of Diamond-Blackfan anemia come into view
In 1938, Louis K. Diamond, MD, and Kenneth Blackfan, MD, at Boston Children’s Hospital described a severe congenital anemia that …Read More
New angles for blocking Shiga and ricin toxins, and new light on an iconic biological process
Min Dong, PhD, and his lab are world experts in toxins and how to combat them. They’ve figured out how Clostridium difficile’s …Read More
Reviving fetal hemoglobin in sickle cell disease: First patient is symptom-free
Manny Johnson of Boston, 21, previously required monthly blood transfusions to keep his severe sickle cell disease under control. After …Read More
Synapse ‘protection’ signal found; helps to refine brain circuits
The developing brain is constantly forming new connections, or synapses, between nerve cells. Many connections are eventually lost, while others …Read More
Creating custom brains from the ground up
Scientists studying how genetics impact brain disease have long sought a better experimental model. Cultures of genetically-modified cell lines can …Read More
Typing medulloblastoma: From RNA to proteomics and phospho-proteomics
Medulloblastoma is one of the most common pediatric brain tumors, accounting for nearly 10 percent of cases. It occurs in the …Read More
Finally in the game: Patient in drug trial for PTEN mutation seems to benefit
From the time of Preston Hall’s birth at 30 weeks, his parents navigated multiple diagnoses, surgeries and sometimes life-threatening medical …Read More
Solving the DIPG puzzle a single cell at a time
For more than 15 years, pediatric neuro-oncologist Mariella Filbin, MD, PhD, has been on a scientific crusade to understand DIPG (diffuse …Read More
Trial shows chemotherapy is helping kids live with pulmonary vein stenosis
Pulmonary vein stenosis (PVS) is a rare disease in which abnormal cells build up inside the veins responsible for carrying oxygen-rich …Read More
Science Seen: New microscope reveals biological life as you’ve never seen it before
Astronomers developed a “guide star” adaptive optics technique to obtain the most crystal-clear and precise telescopic images of distant galaxies, …Read More