Search Results for: daniel kohane
A safe, pain-specific anesthetic shows preclinical promise
All current local anesthetics block sensory signals — pain — but they also interrupt motor signals, which can be problematic. …Read More
Naloxone on demand: Shining a light to reverse opioid overdose
Overdose deaths from fentanyl and other opioids are at record highs in the U.S. Naloxone, if delivered soon after an …Read More
Gold particles and light could melt venous malformations away
Venous malformations — tissues made up largely of abnormally shaped veins — are often difficult to treat, especially when located …Read More
A bio-inspired approach to delivering local anesthetics
Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties. They provide …Read More
An advance for drug-eluting contact lenses: Delivery to the back of the eye
Drug-eluting contact lenses, which gradually release drugs into the eye, offer a promising alternative to daily eye drops, which can …Read More
Opioid alternative? Taming tetrodotoxin for precise painkilling
Opioids remain a mainstay of treatment for chronic and surgical pain, despite their side effects and risk for addiction and …Read More
Using ultrasound to trigger on-demand, site-specific pain relief
According to the CDC, 91 people die from opioid overdoses every day in the U.S. Here in Massachusetts, the state has …Read More
Precision drug delivery systems could ‘trigger’ an age of nanomedicine
What if we could deliver biocompatible nanoparticles into the body and then activate them to release drugs exactly where they …Read More
Drug-eluting contact lens offers hope in glaucoma
Daily medicated eye drops are the first line of treatment for glaucoma, the leading cause of irreversible blindness. The drops …Read More
DIY pain relief with light-activated local nerve blocks
You’ve just had a root canal or knee surgery — both situations that will likely require some sort of local …Read More